Cochrane Review Group

Heart

140 systematic reviews in Heart ask 1,554 questions. 17.5% have no studies to answer them, 21.2% rest on very low certainty evidence and 28.6% reach moderate or high certainty.

Reviews

140

Questions

1,554

current versions

No studies

17.5%

Moderate or high

28.6%

No studies 272 · 17.5%Ungraded 44 · 2.8%Very low 329 · 21.2%Low 464 · 29.9%Moderate 319 · 20.5%High 126 · 8.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Search questions in Heart

Thinnest evidence

All no studies and very low questions

Question	Effect	Evidence	Status / GRADE
Exercise‐based cardiac rehabilitation vs usual care HRQoL (all measurement scales) · adults with heart failure Exercise‐based cardiac rehabilitation for adults with heart failure (2024) · Cochrane	no estimate extracted	33 studies · 4769 participants	Very low
Prophylactic corticosteroids vs placebo or no corticosteroids Length of hospital stay (measured in days, during the index hospital admission) · adults diagnosed with coronary artery disease or cardiac valve disease, and candidates for cardiac surgery with… Prophylactic corticosteroids for cardiopulmonary bypass in adult cardiac surgery (2024) · Cochrane	no estimate extracted	25 studies · 1841 participants	Very low
Mobile phone text messaging vs usual care Medication adherence (self‐reported adherence, questionnaire, tablet counts, medication event monitoring systems, pharmacy prescription data) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	18 studies · 8136 participants	Very low
Mobile phone text messaging vs usual care Non‐fatal cardiovascular events (percentage of people having non‐fatal cardiovascular events) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	NR	Very low
Mobile phone text messaging vs usual care Combined CVD events (percentage of people having combined CVD events) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	NR	Very low
Mobile phone text messaging vs usual care Low‐density lipoprotein cholesterol (mg/dL) (endpoint low‐density lipoprotein cholesterol reading) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	8 studies · 4983 participants	Very low
Mobile phone text messaging vs usual care Blood pressure (mmHg) (endpoint blood pressure reading) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	8 studies · 5173 participants	Very low
Mobile phone text messaging vs usual care Heart rate (beats per minute) (endpoint heart rate reading) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	4 studies · 2946 participants	Very low
Mindfulness‐based interventions (MBIs) vs active comparators Clinical CVD events · people at high risk of or withcardiovascular disease Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	NR	No studies
Mindfulness‐based interventions (MBIs) vs non‐active comparators Clinical CVD events (CVD mortality and non‐fatal MI) · people at high risk of or withcardiovascular disease Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane	RR 0.94 [0.37, 2.42]	1 study · 110 participants	Very low
Transcendental meditation (TM) vs active comparators Perceived stress, change from baseline · people at high risk of or with cardiovascular disease Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	3 studies · 194 participants	Very low
Transcendental meditation (TM) vs active comparators Well‐being · people at high risk of or with cardiovascular disease Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	NR	No studies

Reviews 140

Educational and behavioural interventions for anticoagulant therapy in patients with atrial fibrillation

Clarkesmith, DE, Pattison, HM, et al. · Cochrane Database of Systematic Reviews · 2017

Heart

Thinnest evidence

Reviews 140

Educational and behavioural interventions for anticoagulant therapy in patients with atrial fibrillation

Patient education in the management of coronary heart disease

Niacin for primary and secondary prevention of cardiovascular events

Fixed‐dose combination therapy for the prevention of atherosclerotic cardiovascular diseases

Beta‐blockers for preventing aortic dissection in Marfan syndrome

Vitamin C supplementation for the primary prevention of cardiovascular disease

Exercise‐based cardiac rehabilitation for adults with atrial fibrillation

Prophylactic levosimendan for the prevention of low cardiac output syndrome and mortality in paediatric patients undergoing surgery for congenital heart disease

Remote ischaemic preconditioning for coronary artery bypass grafting (with or without valve surgery)

Ranolazine for stable angina pectoris

Complete versus culprit‐only revascularisation in ST elevation myocardial infarction with multi‐vessel disease

Exercise‐based cardiac rehabilitation in heart transplant recipients

Drug‐eluting stents versus bare‐metal stents for acute coronary syndrome

Antiplatelet versus anticoagulation treatment for patients with heart failure in sinus rhythm

Self‐monitoring and self‐management of oral anticoagulation

Interventions to improve adherence to lipid‐lowering medication

Routine invasive strategies versus selective invasive strategies for unstable angina and non‐ST elevation myocardial infarction in the stent era

Oxygen therapy for acute myocardial infarction

Stem cell therapy for chronic ischaemic heart disease and congestive heart failure

B‐type natriuretic peptide‐guided treatment for heart failure

Pharmacological interventions for treating heart failure in patients with Chagas cardiomyopathy

Chronotherapy versus conventional statins therapy for the treatment of hyperlipidaemia

Statins for aortic valve stenosis

Systematic screening for the detection of atrial fibrillation

Fibrates for primary prevention of cardiovascular disease events