Cochrane · systematic review · CD011851

Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease

Redfern, J, Tu, Q, Hyun, K, et al. · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library

Heart2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 6 · 85.7%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

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Mobile phone text messaging compared to usual care for medication adherence in secondary prevention of cardiovascular disease

Population: people with established arterial occlusive events
7 questions
OutcomeEffectEvidenceStatus / GRADE
Medication adherence (self‐reported adherence, questionnaire, tablet counts, medication event monitoring systems, pharmacy prescription data)
Mobile phone text messaging vs usual care
no estimate extracted18 studies · 8136 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Fatal cardiovascular events (percentage of people having fatal cardiovascular events)
Mobile phone text messaging vs usual care
OR 0.83 [0.47, 1.45]4 studies · 1654 participantsLow
Downgraded: risk of bias, imprecision
Non‐fatal cardiovascular events (percentage of people having non‐fatal cardiovascular events)
Mobile phone text messaging vs usual care
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision, inconsistency
Combined CVD events (percentage of people having combined CVD events)
Mobile phone text messaging vs usual care
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision, inconsistency
Low‐density lipoprotein cholesterol (mg/dL) (endpoint low‐density lipoprotein cholesterol reading)
Mobile phone text messaging vs usual care
no estimate extracted8 studies · 4983 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Blood pressure (mmHg) (endpoint blood pressure reading)
Mobile phone text messaging vs usual care
no estimate extracted8 studies · 5173 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Heart rate (beats per minute) (endpoint heart rate reading)
Mobile phone text messaging vs usual care
no estimate extracted4 studies · 2946 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency