Cochrane Review Group

Heart

140 systematic reviews in Heart ask 1,554 questions. 17.5% have no studies to answer them, 21.2% rest on very low certainty evidence and 28.6% reach moderate or high certainty.

Reviews

140

Questions

1,554

current versions

No studies

17.5%

Moderate or high

28.6%

No studies 272 · 17.5%Ungraded 44 · 2.8%Very low 329 · 21.2%Low 464 · 29.9%Moderate 319 · 20.5%High 126 · 8.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Search questions in Heart

Thinnest evidence

All no studies and very low questions

Question	Effect	Evidence	Status / GRADE
Exercise‐based cardiac rehabilitation vs usual care HRQoL (all measurement scales) · adults with heart failure Exercise‐based cardiac rehabilitation for adults with heart failure (2024) · Cochrane	no estimate extracted	33 studies · 4769 participants	Very low
Prophylactic corticosteroids vs placebo or no corticosteroids Length of hospital stay (measured in days, during the index hospital admission) · adults diagnosed with coronary artery disease or cardiac valve disease, and candidates for cardiac surgery with… Prophylactic corticosteroids for cardiopulmonary bypass in adult cardiac surgery (2024) · Cochrane	no estimate extracted	25 studies · 1841 participants	Very low
Mobile phone text messaging vs usual care Medication adherence (self‐reported adherence, questionnaire, tablet counts, medication event monitoring systems, pharmacy prescription data) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	18 studies · 8136 participants	Very low
Mobile phone text messaging vs usual care Non‐fatal cardiovascular events (percentage of people having non‐fatal cardiovascular events) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	NR	Very low
Mobile phone text messaging vs usual care Combined CVD events (percentage of people having combined CVD events) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	NR	Very low
Mobile phone text messaging vs usual care Low‐density lipoprotein cholesterol (mg/dL) (endpoint low‐density lipoprotein cholesterol reading) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	8 studies · 4983 participants	Very low
Mobile phone text messaging vs usual care Blood pressure (mmHg) (endpoint blood pressure reading) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	8 studies · 5173 participants	Very low
Mobile phone text messaging vs usual care Heart rate (beats per minute) (endpoint heart rate reading) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	4 studies · 2946 participants	Very low
Mindfulness‐based interventions (MBIs) vs active comparators Clinical CVD events · people at high risk of or withcardiovascular disease Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	NR	No studies
Mindfulness‐based interventions (MBIs) vs non‐active comparators Clinical CVD events (CVD mortality and non‐fatal MI) · people at high risk of or withcardiovascular disease Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane	RR 0.94 [0.37, 2.42]	1 study · 110 participants	Very low
Transcendental meditation (TM) vs active comparators Perceived stress, change from baseline · people at high risk of or with cardiovascular disease Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	3 studies · 194 participants	Very low
Transcendental meditation (TM) vs active comparators Well‐being · people at high risk of or with cardiovascular disease Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	NR	No studies

Reviews 140

Exercise‐based cardiac rehabilitation for adults with heart failure

Molloy, C, Long, L, et al. · Cochrane Database of Systematic Reviews · 2024

Heart

Thinnest evidence

Reviews 140

Exercise‐based cardiac rehabilitation for adults with heart failure

Prophylactic corticosteroids for cardiopulmonary bypass in adult cardiac surgery

Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease

Meditation for the primary and secondary prevention of cardiovascular disease

Non‐vitamin‐K‐antagonist oral anticoagulants (NOACs) after acute myocardial infarction: a network meta‐analysis

Continuous infusion versus bolus injection of loop diuretics for acute heart failure

Psychological interventions for depression in adolescent and adult congenital heart disease

Home‐based versus centre‐based cardiac rehabilitation

Limited versus full sternotomy for aortic valve replacement

Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults

Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation

Social network interventions to support cardiac rehabilitation and secondary prevention in the management of people with heart disease

High versus low‐added sugar consumption for the primary prevention of cardiovascular disease

Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk

High versus low blood pressure targets for cardiac surgery while on cardiopulmonary bypass

Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding

Effects of a gluten‐reduced or gluten‐free diet for the primary prevention of cardiovascular disease

Ultrafiltration for acute heart failure

Exercise‐based cardiac rehabilitation for coronary heart disease

Anticoagulation versus placebo for heart failure in sinus rhythm

Antibiotics for secondary prevention of coronary heart disease

Psychological and pharmacological interventions for depression in patients with coronary artery disease

Coenzyme Q10 for heart failure

Exercise‐based cardiac rehabilitation for adults after heart valve surgery

Beta‐blockers in patients without heart failure after myocardial infarction