Cochrane · systematic review · CD013494
High versus low blood pressure targets for cardiac surgery while on cardiopulmonary bypass
Kotani, Y, Kataoka, Y, Izawa, J, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 6 · 85.7%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
High versus low blood pressure target for cardiac surgery with cardiopulmonary bypass
Population: adults undergoing cardiac surgery with cardiopulmonary bypass
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Acute kidney injury High vs low blood pressure target | RR 1.3 [0.81, 2.08] | 2 studies · 487 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Cognitive deterioration High vs low blood pressure target | RR 0.82 [0.45, 1.5] | 2 studies · 389 participants | Low Downgraded: risk of bias, imprecision |
All‐cause mortality High vs low blood pressure target | RR 1.33 [0.3, 5.9] | 3 studies · 737 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Quality of life High vs low blood pressure target | RR 0.78 [0.3, 2.01] | 1 study · 218 participants | Very low Downgraded: risk of bias, imprecision |
Acute ischaemic stroke High vs low blood pressure target | RR 1.29 [0.07, 23.63] | 2 studies · 426 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Length of hospital stay High vs low blood pressure target | no estimate extracted | 2 studies · 540 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Perioperative transfusion of blood products High vs low blood pressure target | no estimate extracted | 2 studies · 540 participants | Very low Downgraded: risk of bias, imprecision |