Cochrane · systematic review · CD013593
Ultrafiltration for acute heart failure
Srivastava, M, Harrison, N, Caetano, AFSMA, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 14.3%Very low 2 · 28.6%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Ultrafiltration (UF) compared to usual care (UC) for acute heart failure (AHF)
Population: people with AHF
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality Ultrafiltration (UF) vs usual care (UC) | RR 0.61 [0.13, 2.85] | 3 studies · 286 participants | Very low Downgraded: risk of bias, imprecision |
All‐cause rehospitalisation Ultrafiltration (UF) vs usual care (UC) | RR 0.76 [0.53, 1.09] | 3 studies · 337 participants | Low Downgraded: risk of bias, imprecision |
Heart failure‐related rehospitalisation Ultrafiltration (UF) vs usual care (UC) | RR 0.62 [0.37, 1.04] | 2 studies · 395 participants | Low Downgraded: risk of bias, imprecision |
Need for mechanical invasive ventilation – up to and including 30 days Ultrafiltration (UF) vs usual care (UC) | no estimate extracted | 0 studies · 0 participants | Ungraded |
% Change in serum creatinine – at 30 days from discharge Ultrafiltration (UF) vs usual care (UC) | no estimate extracted | 1 study · 221 participants | Low Downgraded: risk of bias, imprecision |
New initiation of renal replacement therapy – at longest available Ultrafiltration (UF) vs usual care (UC) | RR 1.42 [0.42, 4.75] | 4 studies · 322 participants | Low Downgraded: imprecision |
Complications of central line insertion – in hospital Ultrafiltration (UF) vs usual care (UC) | RR 4.16 [1.3, 13.3] | 6 studies · 779 participants | Very low Downgraded: risk of bias, imprecision |