Cochrane · systematic review · CD013320

High versus low‐added sugar consumption for the primary prevention of cardiovascular disease

Bergwall, S, Johansson, A, Sonestedt, E, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library

HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
2
Included studies
NR
No studies 2 · 28.6%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 71.4%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Effects of high‐ compared to low‐added sugar consumption for the primary prevention of cardiovascular disease

Population: Adults without diabetes or CVD
7 questions
OutcomeEffectEvidenceStatus / GRADE
Cardiovascular event
Effects of high‐ vs low‐added sugar consumption
no estimate extractedNRNo studies
All‐cause mortality
Effects of high‐ vs low‐added sugar consumption
no estimate extractedNRNo studies
Systolic blood pressure (mmHg)
Effects of high‐ vs low‐added sugar consumption
no estimate extracted14 studies · 873 participantsLow
Downgraded: risk of bias, indirectness
Total cholesterol (mmol/L)
Effects of high‐ vs low‐added sugar consumption
no estimate extracted16 studies · 763 participantsLow
Downgraded: risk of bias, indirectness
LDL‐cholesterol (mmol/L)
Effects of high‐ vs low‐added sugar consumption
no estimate extracted12 studies · 712 participantsLow
Downgraded: risk of bias, indirectness
HDL‐cholesterol (mmol/L)
Effects of high‐ vs low‐added sugar consumption
no estimate extracted16 studies · 817 participantsLow
Downgraded: risk of bias, indirectness
Fasting plasma glucose(mmol/L)
Effects of high‐ vs low‐added sugar consumption
no estimate extracted14 studies · 720 participantsLow
Downgraded: risk of bias, indirectness