Cochrane · systematic review · CD008012
Psychological and pharmacological interventions for depression in patients with coronary artery disease
Tully, PJ, Ang, SY, Lee, EJL, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
20
current version
GRADE rated
9
No studies
6
Included studies
NR
No studies 6 · 30%Ungraded 5 · 25%Very low 4 · 20%Low 4 · 20%Moderate 1 · 5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings table ‐ Psychological treatment compared to control for depression in patients with coronary artery disease
Population: health problem or population
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Depression symptoms ‐ short‐term Summary of findings table ‐ Psychological treatment vs control | no estimate extracted | 10 studies · 1226 participants | Low Downgraded: risk of bias, inconsistency |
Depression remission ‐ short term Summary of findings table ‐ Psychological treatment vs control | OR 2.02 [0.78, 5.19] | 3 studies · 862 participants | Low Downgraded: imprecision, inconsistency |
All‐cause mortality ‐ short‐term Summary of findings table ‐ Psychological treatment vs control | OR 0.31 [0.05, 2.02] | 2 studies · 324 participants | Very low Downgraded: risk of bias, imprecision |
Cardiovascular mortality ‐ long‐term Summary of findings table ‐ Psychological treatment vs control | OR 0.83 [0.62, 1.1] | 2 studies · 2720 participants | Ungraded |
Myocardial infarction ‐ short term (end of treatment) ‐ not reported Summary of findings table ‐ Psychological treatment vs control | no estimate extracted | NR | No studies |
Summary of findings table ‐ Psychological treatment 1 compared to psychological treatment 2 for depression in patients with coronary artery disease
Population: health problem or population
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Depression symptoms ‐ short term (end of treatment) Summary of findings table ‐ Psychological treatment 1 vs psychological treatment 2 | no estimate extracted | 3 studies · 219 participants | Ungraded |
Depression remission ‐ short term (end of treatment) Summary of findings table ‐ Psychological treatment 1 vs psychological treatment 2 | OR 1.81 [0.73, 4.5] | 1 study · 83 participants | Low Downgraded: imprecision |
All‐cause mortality ‐ short term (end of treatment) ‐ not reported Summary of findings table ‐ Psychological treatment 1 vs psychological treatment 2 | no estimate extracted | NR | No studies |
Cardiovascular mortality ‐ short term (end of treatment) ‐ not reported Summary of findings table ‐ Psychological treatment 1 vs psychological treatment 2 | no estimate extracted | NR | No studies |
Myocardial infarction ‐ short term (end of treatment) ‐ not reported Summary of findings table ‐ Psychological treatment 1 vs psychological treatment 2 | no estimate extracted | NR | No studies |
Summary of findings table ‐ Pharmacological treatment compared to placebo for depression in patients with coronary artery disease
Population: health problem or population
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Depression symptoms ‐ short term Summary of findings table ‐ Pharmacological treatment vs placebo | no estimate extracted | 8 studies · 750 participants | Low Downgraded: risk of bias, inconsistency |
Depression remission ‐ short term Summary of findings table ‐ Pharmacological treatment vs placebo | OR 2.06 [1.47, 2.89] | 4 studies · 646 participants | Moderate Downgraded: risk of bias |
All‐cause mortality ‐ short term Summary of findings table ‐ Pharmacological treatment vs placebo | OR 0.38 [0.1, 1.47] | 2 studies · 437 participants | Very low Downgraded: risk of bias, imprecision |
Cardiovascular mortality ‐ short term (end of treatment) ‐ not reported Summary of findings table ‐ Pharmacological treatment vs placebo | no estimate extracted | NR | No studies |
Myocardial infarction ‐ short term Summary of findings table ‐ Pharmacological treatment vs placebo | OR 0.74 [0.26, 2.09] | 3 studies · 728 participants | Very low Downgraded: risk of bias, imprecision |
Summary of findings table ‐ Pharmacological treatment 1 compared to pharmacological treatment 2 for depression in patients with coronary artery disease
Population: health problem or population
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Depression symptoms ‐ short term (end of treatment) Summary of findings table ‐ Pharmacological treatment 1 vs pharmacological treatment 2 | no estimate extracted | 4 studies · 442 participants | Ungraded |
Depression remission ‐ short term (end of treatment) Summary of findings table ‐ Pharmacological treatment 1 vs pharmacological treatment 2 | no estimate extracted | 3 studies · 243 participants | Ungraded |
All‐cause mortality ‐ short term (end of treatment) Summary of findings table ‐ Pharmacological treatment 1 vs pharmacological treatment 2 | OR 2.72 [0.51, 14.49] | 1 study · 149 participants | Very low Downgraded: risk of bias, imprecision |
Cardiovascular mortality ‐ short term (end of treatment) ‐ not reported Summary of findings table ‐ Pharmacological treatment 1 vs pharmacological treatment 2 | no estimate extracted | NR | No studies |
Myocardial infarction ‐ short term (end of treatment) Summary of findings table ‐ Pharmacological treatment 1 vs pharmacological treatment 2 | no estimate extracted | 3 studies · 396 participants | Ungraded |