Cochrane Review Group

Heart

140 systematic reviews in Heart ask 1,554 questions. 17.5% have no studies to answer them, 21.2% rest on very low certainty evidence and 28.6% reach moderate or high certainty.

Reviews

140

Questions

1,554

current versions

No studies

17.5%

Moderate or high

28.6%

No studies 272 · 17.5%Ungraded 44 · 2.8%Very low 329 · 21.2%Low 464 · 29.9%Moderate 319 · 20.5%High 126 · 8.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Search questions in Heart

Thinnest evidence

All no studies and very low questions

Question	Effect	Evidence	Status / GRADE
Exercise‐based cardiac rehabilitation vs usual care HRQoL (all measurement scales) · adults with heart failure Exercise‐based cardiac rehabilitation for adults with heart failure (2024) · Cochrane	no estimate extracted	33 studies · 4769 participants	Very low
Prophylactic corticosteroids vs placebo or no corticosteroids Length of hospital stay (measured in days, during the index hospital admission) · adults diagnosed with coronary artery disease or cardiac valve disease, and candidates for cardiac surgery with… Prophylactic corticosteroids for cardiopulmonary bypass in adult cardiac surgery (2024) · Cochrane	no estimate extracted	25 studies · 1841 participants	Very low
Mobile phone text messaging vs usual care Medication adherence (self‐reported adherence, questionnaire, tablet counts, medication event monitoring systems, pharmacy prescription data) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	18 studies · 8136 participants	Very low
Mobile phone text messaging vs usual care Non‐fatal cardiovascular events (percentage of people having non‐fatal cardiovascular events) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	NR	Very low
Mobile phone text messaging vs usual care Combined CVD events (percentage of people having combined CVD events) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	NR	Very low
Mobile phone text messaging vs usual care Low‐density lipoprotein cholesterol (mg/dL) (endpoint low‐density lipoprotein cholesterol reading) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	8 studies · 4983 participants	Very low
Mobile phone text messaging vs usual care Blood pressure (mmHg) (endpoint blood pressure reading) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	8 studies · 5173 participants	Very low
Mobile phone text messaging vs usual care Heart rate (beats per minute) (endpoint heart rate reading) · people with established arterial occlusive events Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	4 studies · 2946 participants	Very low
Mindfulness‐based interventions (MBIs) vs active comparators Clinical CVD events · people at high risk of or withcardiovascular disease Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	NR	No studies
Mindfulness‐based interventions (MBIs) vs non‐active comparators Clinical CVD events (CVD mortality and non‐fatal MI) · people at high risk of or withcardiovascular disease Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane	RR 0.94 [0.37, 2.42]	1 study · 110 participants	Very low
Transcendental meditation (TM) vs active comparators Perceived stress, change from baseline · people at high risk of or with cardiovascular disease Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	3 studies · 194 participants	Very low
Transcendental meditation (TM) vs active comparators Well‐being · people at high risk of or with cardiovascular disease Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane	no estimate extracted	NR	No studies

Reviews 140

Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation

Valembois, L, Audureau, E, et al. · Cochrane Database of Systematic Reviews · 2019

Heart

Thinnest evidence

Reviews 140

Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation

Non‐invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema

Interventions to promote patient utilisation of cardiac rehabilitation

Mediterranean‐style diet for the primary and secondary prevention of cardiovascular disease

Exercise‐based cardiac rehabilitation for adult patients with an implantable cardioverter defibrillator

Beta‐blockers for suspected or diagnosed acute myocardial infarction

Positive airway pressure therapy for the treatment of central sleep apnoea associated with heart failure

Natriuretic peptide‐guided treatment for the prevention of cardiovascular events in patients without heart failure

Non‐vitamin K antagonist oral anticoagulants (NOACs) post‐percutaneous coronary intervention: a network meta‐analysis

Transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk

Mechanical versus manual chest compressions for cardiac arrest

Omega‐6 fats for the primary and secondary prevention of cardiovascular disease

Exercise‐based cardiac rehabilitation for people with implantable ventricular assist devices

Transradial versus transfemoral approach for diagnostic coronary angiography and percutaneous coronary intervention in people with coronary artery disease

Polyunsaturated fatty acids for the primary and secondary prevention of cardiovascular disease

Ezetimibe for the prevention of cardiovascular disease and all‐cause mortality events

Implantable cardiac defibrillators for people with non‐ischaemic cardiomyopathy

Exercise‐based cardiac rehabilitation for adults with stable angina

Psychological interventions for coronary heart disease

Low glycaemic index diets for the prevention of cardiovascular disease

Whole grain cereals for the primary or secondary prevention of cardiovascular disease

Adenosine versus intravenous calcium channel antagonists for supraventricular tachycardia

Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular events

Homocysteine‐lowering interventions for preventing cardiovascular events

Risk scoring for the primary prevention of cardiovascular disease