Cochrane · systematic review · CD012803
Positive airway pressure therapy for the treatment of central sleep apnoea associated with heart failure
Yamamoto, S, Yamaga, T, Nishie, K, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 5 · 71.4%Moderate 1 · 14.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
PAP therapy compared to usual care for heart failure associated with central sleep apnoea
Population: heart failure associated with central sleep apnoea
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality PAP therapy vs usual care | RR 0.81 [0.54, 1.21] | 6 studies · 1804 participants | Very low Downgraded: risk of bias, inconsistency |
Cardiac‐related mortality PAP therapy vs usual care | RR 0.97 [0.77, 1.24] | 5 studies · 1775 participants | Moderate Downgraded: risk of bias |
All‐cause rehospitalisation PAP therapy vs usual care | RR 0.95 [0.7, 1.3] | 5 studies · 1533 participants | Low Downgraded: risk of bias |
Cardiac‐related rehospitalisation PAP therapy vs usual care | RR 0.97 [0.7, 1.35] | 5 studies · 1533 participants | Low Downgraded: risk of bias |
QOL PAP therapy vs usual care | no estimate extracted | 6 studies · 1617 participants | Low Downgraded: risk of bias, inconsistency |
QOL: Minnesota Living with Heart Failure Questionnaire (MLHFQ) (points) scale from 0 to 105 PAP therapy vs usual care | no estimate extracted | 4 studies · 1458 participants | Low Downgraded: risk of bias, inconsistency |
Adverse events PAP therapy vs usual care | no estimate extracted | 3 studies · 1412 participants | Low Downgraded: risk of bias |