Cochrane · systematic review · CD013319
Transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk
Kolkailah, AA, Doukky, R, Pelletier, MP, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
7
No studies
1
Included studies
NR
No studies 1 · 12.5%Ungraded 0 · 0%Very low 1 · 12.5%Low 1 · 12.5%Moderate 5 · 62.5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Transcatheter aortic valve implantation compared to surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk
Population: adults with severe aortic stenosis who are at a low surgical risk.
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Outcomes (up to 30 days' Transcatheter aortic valve implantation vs surgical aortic valve replacement | no estimate extracted | NR | No studies |
All‐cause mortality Transcatheter aortic valve implantation vs surgical aortic valve replacement | RR 0.69 [0.33, 1.44] | 4 studies · 2818 participants | Moderate Downgraded: imprecision |
Stroke Transcatheter aortic valve implantation vs surgical aortic valve replacement | RR 0.73 [0.42, 1.25] | 4 studies · 2818 participants | Moderate Downgraded: imprecision |
Rehospitalisation Transcatheter aortic valve implantation vs surgical aortic valve replacement | RR 0.64 [0.39, 1.06] | 2 studies · 2468 participants | Low Downgraded: imprecision |
Myocardial infarction Transcatheter aortic valve implantation vs surgical aortic valve replacement | RR 0.82 [0.42, 1.58] | 3 studies · 2748 participants | Moderate Downgraded: imprecision |
Cardiac death Transcatheter aortic valve implantation vs surgical aortic valve replacement | RR 0.71 [0.32, 1.56] | 4 studies · 2818 participants | Moderate Downgraded: imprecision |
Length of hospital stay Transcatheter aortic valve implantation vs surgical aortic valve replacement | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision, inconsistency |
Permanent pacemaker implantation Transcatheter aortic valve implantation vs surgical aortic valve replacement | RR 3.65 [1.5, 8.87] | 3 studies · 2683 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |