Cochrane · systematic review · CD011828

Exercise‐based cardiac rehabilitation for adult patients with an implantable cardioverter defibrillator

Nielsen, KM, Zwisler, AD, Taylor, RS, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
14
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 9 · 64.3%Low 3 · 21.4%Moderate 2 · 14.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Exercise compared to no exercise at the end of the intervention for adults with an implantable cardioverter defibrillator

Population: adult patients with an implantable cardioverter defibrillator
7 questions
OutcomeEffectEvidenceStatus / GRADE
All‐cause mortality (
Exercise vs no exercise at the end of the intervention
RR 1.96 [0.18, 21.26]1 study · 196 participantsLow
Downgraded: imprecision
Serious adverse events (
Exercise vs no exercise at the end of the intervention
RR 1.05 [0.77, 1.44]2 studies · 356 participantsLow
Downgraded: imprecision
Exercise‐capacity (VO2 peak) (
Exercise vs no exercise at the end of the intervention
no estimate extracted7 studies · 1485 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
ICD, antitachycardia pacing (
Exercise vs no exercise at the end of the intervention
RR 1.26 [0.84, 1.9]2 studies · 356 participantsModerate
Downgraded: imprecision
ICD, appropriate shock (
Exercise vs no exercise at the end of the intervention
RR 0.56 [0.2, 1.58]3 studies · 428 participantsLow
Downgraded: risk of bias, imprecision
ICD, inappropriate shock (
Exercise vs no exercise at the end of the intervention
RR 0.6 [0.1, 3.51]1 study · 160 participantsModerate
Downgraded: imprecision
Health‐related quality of life (HRQoL) (
Exercise vs no exercise at the end of the intervention
no estimate extracted5 studies · 433 participantsVery low
Downgraded: risk of bias, inconsistency

Exercise compared to no exercise at longest available follow‐up for adults with an implantable cardioverter defibrillator

Population: adult patients with an implantable cardioverter defibrillator
7 questions
OutcomeEffectEvidenceStatus / GRADE
All‐cause mortality (
Exercise vs no exercise at longest available follow‐up
RR 1.18 [0.65, 2.14]3 studies · 332 participantsVery low
Downgraded: risk of bias, imprecision
Serious adverse events (
Exercise vs no exercise at longest available follow‐up
RR 0.81 [0.61, 1.08]3 studies · 188 participantsVery low
Downgraded: risk of bias, inconsistency
Exercise‐capacity (VO2 peak) (
Exercise vs no exercise at longest available follow‐up
no estimate extracted2 studies · 136 participantsVery low
Downgraded: risk of bias
ICD, antitachycardia pacing (
Exercise vs no exercise at longest available follow‐up
no estimate extracted1 study · 196 participantsVery low
Downgraded: risk of bias, imprecision
ICD, appropriate shock (
Exercise vs no exercise at longest available follow‐up
RR 0.28 [0.05, 1.65]4 studies · 384 participantsVery low
Downgraded: risk of bias, inconsistency
ICD, all shocks (
Exercise vs no exercise at longest available follow‐up
RR 0.89 [0.7, 1.12]1 study · 1053 participantsVery low
Downgraded: risk of bias
HRQoL (
Exercise vs no exercise at longest available follow‐up
no estimate extracted1 study · 52 participantsVery low
Downgraded: risk of bias, imprecision