Cochrane · systematic review · CD005351

Non‐invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema

Berbenetz, N, Wang, Y, Brown, J, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Heart2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 2 · 28.6%Low 2 · 28.6%Moderate 2 · 28.6%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

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NPPV compared to SMC for cardiogenic pulmonary oedema

Population: People with cardiogenic pulmonary oedema
7 questions
OutcomeEffectEvidenceStatus / GRADE
HOSPITAL MORTALITY
NPPV vs SMC
RR 0.65 [0.51, 0.82]21 studies · 2484 participantsLow
Downgraded: risk of bias, imprecision
ETI RATE
NPPV vs SMC
RR 0.49 [0.38, 0.62]20 studies · 2449 participantsModerate
Downgraded: risk of bias
ACUTE MI INCIDENCE
NPPV vs SMC
RR 1.03 [0.91, 1.16]5 studies · 1313 participantsModerate
Downgraded: imprecision
HOSPITAL LENGTH OF STAY
NPPV vs SMC
no estimate extracted11 studies · 1714 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
ICU LENGTH OF STAY
NPPV vs SMC
no estimate extracted6 studies · 587 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
INTOLERANCE TO ALLOCATED TREATMENT ‐ not reported
NPPV vs SMC
no estimate extractedNRNo studies
ADVERSE EVENTS
NPPV vs SMC
no estimate extracted11 studies · 2038 participantsLow
Downgraded: risk of bias, imprecision