Cochrane · systematic review · CD003333
Antiplatelet versus anticoagulation treatment for patients with heart failure in sinus rhythm
Shantsila, E, Lip, GYH · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 50%Moderate 3 · 50%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings: warfarin versus aspirin for heart failure with sinus rhythm
Population: patients with heart failure with sinus rhythm
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality Summary of findings: warfarin vs aspirin | RR 1 [0.89, 1.13] | 4 studies · 3663 participants | Moderate Downgraded: imprecision |
Non‐fatal cardiovascular events (non‐fatal stroke, myocardial infarction, pulmonary embolism, peripheral arterial embolism) Summary of findings: warfarin vs aspirin | RR 0.79 [0.63, 1] | 4 studies · 3663 participants | Moderate Downgraded: imprecision |
Major bleeding events Summary of findings: warfarin vs aspirin | RR 2 [1.44, 2.78] | 4 studies · 3663 participants | Moderate Downgraded: imprecision |
Summary of findings: warfarin versus clopidogrel for heart failure with sinus rhythm
Population: patients with heart failure with sinus rhythm
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality Summary of findings: warfarin vs clopidogrel | RR 0.93 [0.72, 1.21] | 1 study · 1064 participants | Low Downgraded: imprecision |
Non‐fatal cardiovascular events (non‐fatal stroke, myocardial infarction, pulmonary embolism, peripheral arterial embolism) Summary of findings: warfarin vs clopidogrel | RR 0.85 [0.5, 1.45] | 1 study · 1064 participants | Low Downgraded: imprecision |
Major bleeding events Summary of findings: warfarin vs clopidogrel | RR 2.47 [1.24, 4.91] | 1 study · 1064 participants | Low Downgraded: imprecision |