Cochrane · systematic review · CD007160
Oxygen therapy for acute myocardial infarction
Cabello, JB, Burls, A, Emparanza, JI, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 42.9%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Oxygen versus air for acute myocardial infarction
Population: people with acute myocardial infarction
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality in hospital for participants with AMI Oxygen vs air | RR 1.02 [0.52, 1.98] | 4 studies · 871 participants | Very low Downgraded: risk of bias, imprecision |
All‐cause mortality in hospital for all participants (including those without confirmed AMI) Oxygen vs air | RR 0.99 [0.5, 1.95] | 4 studies · 1123 participants | Very low Downgraded: imprecision |
All‐cause mortality in hospital for all participants (including those without confirmed AMI) trials done in the revascularisation era Oxygen vs air | RR 0.58 [0.24, 1.39] | 3 studies · 923 participants | Low Downgraded: imprecision |
Opiate use (as a proxy measure for pain) for all participants on ITT (including those without confirmed AMI) Oxygen vs air | RR 0.97 [0.78, 1.2] | 2 studies · 250 participants | Low Downgraded: risk of bias, indirectness |
Recurrent myocardial infarction (or ischaemia) Oxygen vs air | RR 1.67 [0.94, 2.99] | 2 studies · 578 participants | Low Downgraded: imprecision, inconsistency |
Infarct size CK and other enzymes Oxygen vs air | no estimate extracted | 0 studies · 2 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Infarct size by MRI (estimated 6 months after AMI) Oxygen vs air | no estimate extracted | 0 studies · 2 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |