Cochrane · systematic review · CD004371

Interventions to improve adherence to lipid‐lowering medication

van Driel, ML, Morledge, MD, Ulep, R, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 20%Moderate 2 · 40%High 2 · 40%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings table for the comparison of 'intensified patient care' vs 'usual care'

Population: People receiving lipid‐lowering medications
5 questions
OutcomeEffectEvidenceStatus / GRADE
Medication adherence at ≤ 6 months
Summary of findings table for the comparison of 'intensified patient care' vs 'usual care'
OR 1.93 [1.29, 2.88]7 studies · 11204 participantsModerate
Downgraded: inconsistency
Medication adherence at > 6 months
Summary of findings table for the comparison of 'intensified patient care' vs 'usual care'
OR 2.87 [1.91, 4.29]3 studies · 663 participantsHigh
Reduction in LDL‐C at ≤ 6 months (mg/dL)
Summary of findings table for the comparison of 'intensified patient care' vs 'usual care'
no estimate extracted3 studies · 333 participantsModerate
Downgraded: inconsistency
Reduction in total serum cholesterol at ≤ 6 months (mg/dL)
Summary of findings table for the comparison of 'intensified patient care' vs 'usual care'
no estimate extracted4 studies · 430 participantsLow
Downgraded: imprecision, inconsistency
Reduction in total serum cholesterol at > 6 mos (mg/dL)
Summary of findings table for the comparison of 'intensified patient care' vs 'usual care'
no estimate extracted2 studies · 127 participantsHigh