Cochrane · systematic review · CD011719
Remote ischaemic preconditioning for coronary artery bypass grafting (with or without valve surgery)
Benstoem, C, Stoppe, C, Liakopoulos, OJ, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 6 · 85.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
RIPC versus no RIPC in people undergoing CABG (with or without valve surgery)
Population: people undergoing CABG (with or without valve surgery)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Composite endpoint (including all‐cause mortality, non‐fatal myocardial infarction and/or any new stroke assessed at 30 days after surgery) RIPC vs no RIPC | RR 0.99 [0.78, 1.25] | 2 studies · 2463 participants | Moderate Downgraded: imprecision |
Cardiac troponin T (cTnT) RIPC vs no RIPC | no estimate extracted | 4 studies · 1792 participants | Low Downgraded: imprecision, inconsistency |
cTnT 72 h after surgery (ng/L) RIPC vs no RIPC | no estimate extracted | 3 studies · 1120 participants | Moderate Downgraded: inconsistency |
cTnT AUC 72 h (ng/L) RIPC vs no RIPC | no estimate extracted | 3 studies · 830 participants | Moderate Downgraded: inconsistency |
Cardiac troponin I (cTnI) RIPC vs no RIPC | no estimate extracted | 5 studies · 745 participants | Moderate Downgraded: inconsistency |
cTnI 72 h after surgery (ng/L) RIPC vs no RIPC | no estimate extracted | 2 studies · 459 participants | Moderate Downgraded: risk of bias, imprecision |
cTnI AUC 72 h (ng/L) RIPC vs no RIPC | no estimate extracted | 2 studies · 159 participants | Moderate Downgraded: imprecision |