Cochrane · systematic review · CD009462
Chronotherapy versus conventional statins therapy for the treatment of hyperlipidaemia
Izquierdo‐Palomares, JM, Fernandez‐Tabera, JM, Plana, MN, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 28.6%Very low 0 · 0%Low 5 · 71.4%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Chronotherapy for the treatment of hyperlipidaemia
Population: people with hyperlipidaemia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Cardiovascular mortality | no estimate extracted | 0 studies · 0 participants | Ungraded |
Cardiovacular morbidity | no estimate extracted | 0 studies · 0 participants | Ungraded |
At least 1 adverse event | OR 0.71 [0.44, 1.15] | 5 studies · 556 participants | Low Downgraded: risk of bias, imprecision |
Total Cholesterol (mg/dL) | no estimate extracted | 5 studies · 514 participants | Low Downgraded: risk of bias, imprecision |
LDL‐C (mg/dL) | no estimate extracted | 5 studies · 473 participants | Low Downgraded: risk of bias, imprecision |
HDL‐C (mg/dL) | no estimate extracted | 5 studies · 514 participants | Low Downgraded: risk of bias, imprecision |
Triglycerides (mg/dL) | no estimate extracted | 5 studies · 510 participants | Low Downgraded: risk of bias, imprecision |