Cochrane Review Group
Pain, Palliative and Supportive Care
147 systematic reviews in Pain, Palliative and Supportive Care ask 1,751 questions. 20.6% have no studies to answer them, 35.7% rest on very low certainty evidence and 17.7% reach moderate or high certainty.
Reviews
147
Questions
1,751
current versions
No studies
20.6%
Moderate or high
17.7%
No studies 361 · 20.6%Ungraded 87 · 5%Very low 625 · 35.7%Low 367 · 21%Moderate 232 · 13.2%High 79 · 4.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Thinnest evidence
All no studies and very low questions| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Summary of findings table ‐ Gabapentin vs pregabalin Risk for at least one adverse event per patient · patients with chronic kidney disease (CKD) pruritus Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | RR 4.7 [0.21, 104.14] | 2 studies · 122 participants | Very low |
Summary of findings table ‐ Kappa‐opioid agonists vs placebo Quality of life ‐ not measured · patients with chronic kidney disease (CKD) pruritus Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Kappa‐opioid agonists vs placebo Patient satisfaction ‐ not measured · patients with chronic kidney disease (CKD) pruritus Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Kappa‐opioid agonists vs placebo Depression ‐ not measured · patients with chronic kidney disease (CKD) pruritus Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Ondansetron vs placebo Quality of life ‐ not measured · patients with chronic kidney disease (CKD) pruritus Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Ondansetron vs placebo Patient satisfaction ‐ not measured · patients with chronic kidney disease (CKD) pruritus Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Ondansetron vs placebo Depression ‐ not measured · patients with chronic kidney disease (CKD) pruritus Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ GABA‐analogues vs placebo Quality of life ‐ not measured · health problem or population Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Ondansetron vs placebo Risk for at least one adverse event per patient · patients with chronic kidney disease (CKD) pruritus Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | RR 2.54 [0.38, 16.78] | 3 studies · 174 participants | Very low |
Summary of findings table ‐ Montelukast vs placebo Pruritus · patients with chronic kidney disease (CKD) pruritus Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | no estimate extracted | 2 studies · 87 participants | Very low |
Summary of findings table ‐ Montelukast vs placebo Quality of life ‐ not measured · patients with chronic kidney disease (CKD) pruritus Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Montelukast vs placebo Patient satisfaction ‐ not measured · patients with chronic kidney disease (CKD) pruritus Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | no estimate extracted | NR | No studies |
Reviews 147
Interventions for the management of malignant pleural effusions: a network meta‐analysis
CochraneSoF table
42 questions
Virtual reality distraction for acute pain in children
CochraneSoF table
21 questions
The effectiveness and cost‐effectiveness of hospital‐based specialist palliative care for adults with advanced illness and their caregivers
CochraneSoF table
7 questions
Pregabalin for neuropathic pain in adults
CochraneSoF table
33 questions
Psychological interventions for parents of children and adolescents with chronic illness
CochraneSoF table
24 questions
Herbal medicinal products or preparations for neuropathic pain
CochraneSoF table
7 questions
Psychological therapies (remotely delivered) for the management of chronic and recurrent pain in children and adolescents
CochraneSoF table
14 questions
Pharmacological interventions for painful sickle cell vaso‐occlusive crises in adults
CochraneSoF table
21 questions
Psychological therapies for the prevention of migraine in adults
CochraneSoF table
6 questions
Continuous local anaesthetic wound infusion for postoperative pain after midline laparotomy for colorectal resection in adults
CochraneSoF table
6 questions
Systemic corticosteroids for the management of cancer‐related breathlessness (dyspnoea) in adults
CochraneSoF table
6 questions
Psychological therapies for the management of chronic and recurrent pain in children and adolescents
CochraneSoF table
15 questions
Psychological interventions for needle‐related procedural pain and distress in children and adolescents
CochraneSoF table
42 questions
Non‐invasive brain stimulation techniques for chronic pain
CochraneSoF table
9 questions
Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia
CochraneSoF table
7 questions
Combination pharmacotherapy for the treatment of fibromyalgia in adults
CochraneSoF table
7 questions
Needle size for vaccination procedures in children and adolescents
CochraneSoF table
33 questions
Botulinum toxins for the prevention of migraine in adults
CochraneSoF table
13 questions
Exercise for reducing falls in people living with and beyond cancer
CochraneSoF table
7 questions
Oral water soluble contrast for malignant bowel obstruction
CochraneSoF table
7 questions
Perioperative intravenous ketamine for acute postoperative pain in adults
CochraneSoF table
6 questions
Cannabis‐based medicines for chronic neuropathic pain in adults
CochraneSoF table
7 questions
Ghrelin for the management of cachexia associated with cancer
CochraneSoF table
12 questions
Ketorolac for postoperative pain in children
CochraneSoF table
7 questions
Single‐dose intravenous diclofenac for acute postoperative pain in adults
CochraneSoF table
12 questions