Cochrane · systematic review · CD012310
Continuous local anaesthetic wound infusion for postoperative pain after midline laparotomy for colorectal resection in adults
Liang, SS, Ying, AJ, Affan, ET, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
Pain, Palliative and Supportive CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 33.3%Moderate 2 · 33.3%High 2 · 33.3%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Continuous local anaesthetic wound infusion compared to placebo for postoperative pain after midline laparotomy for colorectal resection in adults
Population: adults undergoing elective midline laparotomy for colorectal resection
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain score at rest postoperative day 1 Continuous local anaesthetic wound infusion vs placebo | no estimate extracted | 5 studies · 511 participants | High |
Pain score on movement postoperative day 1 Continuous local anaesthetic wound infusion vs placebo | no estimate extracted | 3 studies · 407 participants | Low Downgraded: risk of bias, inconsistency |
Opioid consumption via patient controlled analgesia postoperative day 1 Continuous local anaesthetic wound infusion vs placebo | no estimate extracted | 6 studies · 528 participants | Moderate Downgraded: risk of bias |
Time to first bowel movement (days) Continuous local anaesthetic wound infusion vs placebo | no estimate extracted | 4 studies · 197 participants | Moderate Downgraded: imprecision |
Length of hospital stay (days) Continuous local anaesthetic wound infusion vs placebo | no estimate extracted | 4 studies · 456 participants | High |
Any serious postoperative adverse event (until hospital discharge) Continuous local anaesthetic wound infusion vs placebo | RR 1.04 [0.68, 1.58] | 6 studies · 541 participants | Low Downgraded: risk of bias, indirectness |