Cochrane Review Group

Pain, Palliative and Supportive Care

147 systematic reviews in Pain, Palliative and Supportive Care ask 1,751 questions. 20.6% have no studies to answer them, 35.7% rest on very low certainty evidence and 17.7% reach moderate or high certainty.

Reviews
147
Questions
1,751
current versions
No studies
20.6%
Moderate or high
17.7%
No studies 361 · 20.6%Ungraded 87 · 5%Very low 625 · 35.7%Low 367 · 21%Moderate 232 · 13.2%High 79 · 4.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Summary of findings table ‐ Gabapentin vs pregabalin
Risk for at least one adverse event per patient · patients with chronic kidney disease (CKD) pruritus
Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane
RR 4.7 [0.21, 104.14]2 studies · 122 participantsVery low
Summary of findings table ‐ Kappa‐opioid agonists vs placebo
Quality of life ‐ not measured · patients with chronic kidney disease (CKD) pruritus
Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Kappa‐opioid agonists vs placebo
Patient satisfaction ‐ not measured · patients with chronic kidney disease (CKD) pruritus
Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Kappa‐opioid agonists vs placebo
Depression ‐ not measured · patients with chronic kidney disease (CKD) pruritus
Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Ondansetron vs placebo
Quality of life ‐ not measured · patients with chronic kidney disease (CKD) pruritus
Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Ondansetron vs placebo
Patient satisfaction ‐ not measured · patients with chronic kidney disease (CKD) pruritus
Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Ondansetron vs placebo
Depression ‐ not measured · patients with chronic kidney disease (CKD) pruritus
Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ GABA‐analogues vs placebo
Quality of life ‐ not measured · health problem or population
Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Ondansetron vs placebo
Risk for at least one adverse event per patient · patients with chronic kidney disease (CKD) pruritus
Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane
RR 2.54 [0.38, 16.78]3 studies · 174 participantsVery low
Summary of findings table ‐ Montelukast vs placebo
Pruritus · patients with chronic kidney disease (CKD) pruritus
Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane
no estimate extracted2 studies · 87 participantsVery low
Summary of findings table ‐ Montelukast vs placebo
Quality of life ‐ not measured · patients with chronic kidney disease (CKD) pruritus
Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Montelukast vs placebo
Patient satisfaction ‐ not measured · patients with chronic kidney disease (CKD) pruritus
Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane
no estimate extractedNRNo studies

Reviews 147

Pharmacological interventions for pruritus in adult palliative care patients

Boehlke, C, Joos, L, et al. · Cochrane Database of Systematic Reviews · 2024
CochraneSoF table
61 questions

Ibuprofen for acute postoperative pain in children

Pessano, S, Gloeck, NR, et al. · Cochrane Database of Systematic Reviews · 2024
CochraneSoF table
24 questions

Medically assisted hydration for adults receiving palliative care

Buchan, EJ, Haywood, A, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
6 questions

Non‐pharmacological management of infant and young child procedural pain

Pillai Riddell, RR, Bucsea, O, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
15 questions

Interventions for the symptoms and signs resulting from jellyfish stings

McGee, RG, Webster, AC, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
14 questions

Physical activity and education about physical activity for chronic musculoskeletal pain in children and adolescents

Nascimento Leite, M, Kamper, SJ, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
18 questions

Corticosteroids for the management of cancer‐related fatigue in adults with advanced cancer

Sandford, A, Haywood, A, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
8 questions

Psychological therapies delivered remotely for the management of chronic pain (excluding headache) in adults

Rosser, BA, Fisher, E, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
24 questions

Antidepressants for pain management in adults with chronic pain: a network meta‐analysis

Birkinshaw, H, Friedrich, CM, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
30 questions

Cannabis‐based medicines and medical cannabis for adults with cancer pain

Häuser, W, Welsch, P, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
7 questions

Diclofenac for acute postoperative pain in children

Ringsten, M, Kredo, T, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
32 questions

Oxycodone for cancer‐related pain

Schmidt-Hansen, M, Bennett, MI, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
15 questions

Mu‐opioid antagonists for opioid‐induced bowel dysfunction in people with cancer and people receiving palliative care

Candy, B, Jones, L, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
36 questions

Physiotherapy for pain and disability in adults with complex regional pain syndrome (CRPS) types I and II

Smart, KM, Ferraro, MC, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
6 questions

Topical clonidine for neuropathic pain in adults

Serednicki, WT, Wrzosek, A, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
14 questions

Prophylactic antiemetics for adults receiving intravenous opioids in the acute care setting

Gottlieb, M, Carlson, JN, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
6 questions

Exercise for cancer cachexia in adults

Grande, AJ, Silva, V, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
14 questions

Hydromorphone for cancer pain

Li, Y, Ma, J, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
21 questions

Antiemetics for adults for prevention of nausea and vomiting caused by moderately or highly emetogenic chemotherapy: a network meta‐analysis

Piechotta, V, Adams, A, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
36 questions

Single‐dose intravenous ketorolac for acute postoperative pain in adults

McNicol, ED, Ferguson, MC, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
12 questions

Single‐dose intravenous ibuprofen for acute postoperative pain in adults

Ferguson, MC, Schumann, R, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
12 questions

Implanted spinal neuromodulation interventions for chronic pain in adults

O'Connell, NE, Ferraro, MC, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
27 questions

Interventions for palliative symptom control in COVID‐19 patients

Andreas, M, Piechotta, V, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
9 questions

Drug therapy for delirium in terminally ill adults

Finucane, AM, Jones, L, et al. · Cochrane Database of Systematic Reviews · 2020
CochraneSoF table
40 questions

Psychological therapies for the management of chronic pain (excluding headache) in adults

Williams, AC de C, Fisher, E, et al. · Cochrane Database of Systematic Reviews · 2020
CochraneSoF table
14 questions