Cochrane · systematic review · CD013782
Corticosteroids for the management of cancer‐related fatigue in adults with advanced cancer
Sandford, A, Haywood, A, Rickett, K, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
Pain, Palliative and Supportive CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
8
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 8 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Corticosteroids compared with placebo for the management of cancer‐related fatigue
Population: adults with advanced cancer and cancer‐related fatigue
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Fatigue relief ( Corticosteroids vs placebo | no estimate extracted | 3 studies · 165 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Adverse events Corticosteroids vs placebo | no estimate extracted | 3 studies · 165 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Serious adverse events Corticosteroids vs placebo | no estimate extracted | 2 studies · 118 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Quality of life (QoL) ( Corticosteroids vs placebo | no estimate extracted | 2 studies · 118 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Corticosteroids compared with modafinil for the management of cancer‐related fatigue
Population: adults with advanced cancer and cancer‐related fatigue
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Fatigue relief ( Corticosteroids vs modafinil | no estimate extracted | 1 study · 73 participants | Very low Downgraded: risk of bias, imprecision |
Adverse events Corticosteroids vs modafinil | no estimate extracted | 1 study · 73 participants | Very low Downgraded: risk of bias, imprecision |
Serious adverse events Corticosteroids vs modafinil | no estimate extracted | 1 study · 73 participants | Very low Downgraded: risk of bias, imprecision |
Quality of life ( Corticosteroids vs modafinil | no estimate extracted | 1 study · 73 participants | Very low Downgraded: risk of bias, imprecision |