Cochrane · systematic review · CD006273

Medically assisted hydration for adults receiving palliative care

Buchan, EJ, Haywood, A, Syrmis, W, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
5
No studies
1
Included studies
NR
No studies 1 · 16.7%Ungraded 0 · 0%Very low 5 · 83.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Medically assisted hydration compared with placebo for adults receiving palliative care

Population: adults aged 18 years and older receiving palliative care
3 questions
OutcomeEffectEvidenceStatus / GRADE
Quality of life FACT‐G (scale from 0 to 108; higher score = better QoL)
Medically assisted hydration vs placebo
no estimate extracted1 study · 93 participantsVery low
Downgraded: imprecision, indirectness
Survival Log‐rank analysis Study enrolment to last date of
Medically assisted hydration vs placebo
no estimate extracted1 study · 93 participantsVery low
Downgraded: imprecision, indirectness
Adverse events NRS (scale from 0 to 10; lower score = less toxicity)
Medically assisted hydration vs placebo
no estimate extracted1 study · 49 participantsVery low
Downgraded: imprecision, indirectness

Medically assisted hydration compared with standard care for adults receiving palliative care

Population: adults aged 18 years and older receiving palliative care
3 questions
OutcomeEffectEvidenceStatus / GRADE
Quality of life
Medically assisted hydration vs standard care
no estimate extractedNRNo studies
Survival Cox regression model Study enrolment to last date of
Medically assisted hydration vs standard care
no estimate extracted1 study · 200 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Adverse events Participant events
Medically assisted hydration vs standard care
no estimate extracted2 studies · 242 participantsVery low
Downgraded: risk of bias, imprecision, indirectness