Cochrane · systematic review · CD010804
Exercise for cancer cachexia in adults
Grande, AJ, Silva, V, Sawaris Neto, L, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
Pain, Palliative and Supportive CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
11
No studies
3
Included studies
NR
No studies 3 · 21.4%Ungraded 0 · 0%Very low 11 · 78.6%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Exercise plus usual care compared to usual care for cancer cachexia in adults
Population: cancer cachexia in adults
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Lean body mass Exercise plus usual care vs usual care | no estimate extracted | 1 study · 20 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Adherence to prescribed exercise programmes Exercise plus usual care vs usual care | RR 1 | 1 study · 20 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Occurrence of adverse events Exercise plus usual care vs usual care | no estimate extracted | 1 study · 20 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Muscle strength and endurance Exercise plus usual care vs usual care | no estimate extracted | NR | No studies |
Maximal and submaximal exercise capacity Functional capacity Exercise plus usual care vs usual care | no estimate extracted | NR | No studies |
Fatigue Exercise plus usual care vs usual care | no estimate extracted | 1 study · 20 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Health‐related quality of life Exercise plus usual care vs usual care | no estimate extracted | 1 study · 20 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Multimodal intervention (exercise plus other interventions) plus usual care compared to usual care
Population: cancer cachexia in adults
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Lean body mass Multimodal intervention (exercise plus other interventions) plus usual care vs usual care | no estimate extracted | 1 study · 44 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Adherence to prescribed exercise programmes Multimodal intervention (exercise plus other interventions) plus usual care vs usual care | no estimate extracted | NR | No studies |
Occurrence of adverse events Multimodal intervention (exercise plus other interventions) plus usual care vs usual care | RR 1.18 [0.67, 2.07] | 1 study · 44 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Muscle strength and endurance** Strength Multimodal intervention (exercise plus other interventions) plus usual care vs usual care | no estimate extracted | 1 study · 44 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Maximal and submaximal exercise capacity** Submaximal capacity Multimodal intervention (exercise plus other interventions) plus usual care vs usual care | no estimate extracted | 1 study · 44 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Fatigue Multimodal intervention (exercise plus other interventions) plus usual care vs usual care | no estimate extracted | 1 study · 44 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Health‐related quality of life Multimodal intervention (exercise plus other interventions) plus usual care vs usual care | no estimate extracted | 1 study · 60 participants | Very low Downgraded: risk of bias, imprecision, indirectness |