Cochrane · systematic review · CD007407

Psychological therapies for the management of chronic pain (excluding headache) in adults

Williams, AC de C, Fisher, E, Hearn, L, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
14
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 14.3%Low 3 · 21.4%Moderate 9 · 64.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings: CBT compared with AC for adults with chronic pain

Population: Adults with chronic pain (excluding headache)
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain intensity at the end of treatment as measured by multiple scales including VAS, BPI, AIMS, numerical rating scale, MPI Higher scores indicate higher pain intensity
Summary of findings: CBT vs AC
no estimate extracted23 studies · 3235 participantsModerate
Downgraded: risk of bias
Pain intensity at
Summary of findings: CBT vs AC
no estimate extracted16 studies · 2362 participantsModerate
Downgraded: risk of bias
Disability at the end of treatment as measured by multiple scales including RMDQ, AIMS Higher scores indicate higher levels of disability
Summary of findings: CBT vs AC
no estimate extracted19 studies · 2543 participantsModerate
Downgraded: risk of bias
Disability at
Summary of findings: CBT vs AC
no estimate extracted15 studies · 1919 participantsLow
Downgraded: risk of bias
Distress at the end of treatment as measured by multiple scales including BDI, DASS and CES‐D Higher scores indicate higher levels of distress
Summary of findings: CBT vs AC
no estimate extracted24 studies · 3297 participantsModerate
Downgraded: risk of bias
Distress at
Summary of findings: CBT vs AC
no estimate extracted16 studies · 2363 participantsModerate
Downgraded: risk of bias
Adverse events Higher scores indicate higher numbers of AEs
Summary of findings: CBT vs AC
no estimate extracted3 studies · 689 participantsVery low
Downgraded: risk of bias, inconsistency, indirectness

Summary of findings: CBT compared with TAU for adults with chronic pain

Population: Adults with chronic pain (excluding headache)
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain intensity at the end of treatment as measured by multiple scales including VAS, BPI, AIMS, numerical rating scale, MPI Higher scores indicate higher pain intensity
Summary of findings: CBT vs TAU
no estimate extracted29 studies · 2572 participantsModerate
Downgraded: risk of bias
Pain intensity at
Summary of findings: CBT vs TAU
no estimate extracted15 studies · 1674 participantsModerate
Downgraded: risk of bias
Disability at the end of treatment as measured by multiple scales including AIMS, ODI, FIQ, MPI Higher scores indicate higher levels of disability
Summary of findings: CBT vs TAU
no estimate extracted28 studies · 2524 participantsLow
Downgraded: risk of bias
Disability at
Summary of findings: CBT vs TAU
no estimate extracted15 studies · 1581 participantsLow
Downgraded: risk of bias
Distress at the end of treatment as measured by multiple scales including BDI, CES‐D, SCL‐90R, HADS Higher scores indicate higher levels of distress
Summary of findings: CBT vs TAU
no estimate extracted27 studies · 2559 participantsModerate
Downgraded: risk of bias
Distress at
Summary of findings: CBT vs TAU
no estimate extracted16 studies · 1757 participantsModerate
Downgraded: risk of bias
Adverse events Higher scores indicate higher numbers of AEs
Summary of findings: CBT vs TAU
no estimate extracted8 studies · 1314 participantsVery low
Downgraded: risk of bias, inconsistency, indirectness