Cochrane · systematic review · CD010528
Herbal medicinal products or preparations for neuropathic pain
Boyd, A, Bleakley, C, Hurley, DA, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
Pain, Palliative and Supportive CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
3
Included studies
NR
No studies 3 · 42.9%Ungraded 0 · 0%Very low 4 · 57.1%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Herbal treatment compared with placebo for adults with neuropathic pain
Population: adults with neuropathic pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Participant‐reported pain relief of 30% or greater Immediately post‐intervention Herbal treatment vs placebo | RR 1.12 [0.69, 1.85] | 1 study · 74 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Participant‐reported pain relief of 50% or greater Immediately post‐intervention Herbal treatment vs placebo | no estimate extracted | NR | No studies |
Participant‐reported global impression of clinical change (PGIC) much or very much improved (moderate) Immediately post‐intervention Herbal treatment vs placebo | no estimate extracted | NR | No studies |
Participant‐reported global impression of clinical change (PGIC) very much improved (substantial) Immediately post‐intervention Herbal treatment vs placebo | no estimate extracted | NR | No studies |
Any pain‐related outcome indicating some improvement VAS 1‐100 Immediately post‐intervention (high score indicates more pain relief) Herbal treatment vs placebo | no estimate extracted | 1 study · 74 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Study withdrawals Post‐intervention Herbal treatment vs placebo | RR 0.83 [0.26, 2.64] | 2 studies · 128 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Adverse events Post‐intervention Herbal treatment vs placebo | RR 1 [0.55, 1.81] | 2 studies · 128 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |