Cochrane · systematic review · CD012014

Oral water soluble contrast for malignant bowel obstruction

Syrmis, W, Richard, R, Jenkins-Marsh, S, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
2
No studies
5
Included studies
NR
No studies 5 · 71.4%Ungraded 0 · 0%Very low 2 · 28.6%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings

Population: Adults 18 yrs and over with malignant bowel obstruction (MBO) as defined by the International Conference on MBO, with no indication for other treatments e.g. surgery, endoscopy, etc
7 questions
OutcomeEffectEvidenceStatus / GRADE
The ability of OWSC, when seen to reach the colon on
no estimate extractedNRNo studies
The rate of resolution of MBO with medical management only in patients receiving OWSC compared with those not receiving it (therapeutic).
no estimate extractedNRNo studies
Gastrointestinal adverse effects (increased abdominal pain, nausea, vomiting).
no estimate extracted1 study · 9 participantsVery low
Downgraded: risk of bias, imprecision
Extra‐abdominal complications (aspiration pneumonia, hypersensitivity reactions).
no estimate extracted1 study · 9 participantsVery low
Downgraded: risk of bias, imprecision
Length of hospital stay.
no estimate extractedNRNo studies
Time from administration of OWSC to resolution of MBO.
no estimate extractedNRNo studies
Survival time from onset of inoperable MBO until death.
no estimate extractedNRNo studies