Cochrane Review Group

Anaesthesia

125 systematic reviews in Anaesthesia ask 1,463 questions. 13.5% have no studies to answer them, 21% rest on very low certainty evidence and 21.5% reach moderate or high certainty.

Reviews

125

Questions

1,463

current versions

No studies

13.5%

Moderate or high

21.5%

No studies 197 · 13.5%Ungraded 203 · 13.9%Very low 307 · 21%Low 441 · 30.1%Moderate 245 · 16.7%High 70 · 4.8%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Search questions in Anaesthesia

Thinnest evidence

All no studies and very low questions

Question	Effect	Evidence	Status / GRADE
Summary of findings ‐ Erector spinae plane block vs intercostal nerve block Mean difference in postoperative pain intensity at rest 24 hours postoperatively (VAS 0 to 10) · adults undergoing surgery with general anaesthesia Erector spinae plane block for postoperative pain (2024) · Cochrane	no estimate extracted	2 studies · 131 participants	Very low
Summary of findings ‐ Erector spinae plane block vs intercostal nerve block Rates of block‐related adverse events · adults undergoing surgery with general anaesthesia Erector spinae plane block for postoperative pain (2024) · Cochrane	RR 0.09 [0.04, 2.28]	3 studies · 181 participants	Very low
Summary of findings ‐ Erector spinae plane block vs epidural analgesia Mean difference in postoperative pain intensity at rest 24 hours postoperatively (VAS 0 to 10) · adults undergoing surgery with general anaesthesia Erector spinae plane block for postoperative pain (2024) · Cochrane	no estimate extracted	2 studies · 81 participants	Very low
Hyperangulated videolaryngoscopy vs direct laryngoscopy Dental trauma · adults undergoing tracheal intubation Videolaryngoscopy versus direct laryngoscopy for adults undergoing tracheal intubation (2022) · Cochrane	RR 0.51 [0.16, 1.59]	30 studies · 3497 participants	Very low
Hyperangulated videolaryngoscopy vs direct laryngoscopy Time for tracheal intubation · adults undergoing tracheal intubation Videolaryngoscopy versus direct laryngoscopy for adults undergoing tracheal intubation (2022) · Cochrane	no estimate extracted	59 studies · 6644 participants	Very low
Channelled videolaryngoscopy vs direct laryngoscopy Successful first attempt · adults undergoing tracheal intubation Videolaryngoscopy versus direct laryngoscopy for adults undergoing tracheal intubation (2022) · Cochrane	RR 1.1 [1.05, 1.15]	47 studies · 5210 participants	Very low
Channelled videolaryngoscopy vs direct laryngoscopy Dental trauma · adults undergoing tracheal intubation Videolaryngoscopy versus direct laryngoscopy for adults undergoing tracheal intubation (2022) · Cochrane	RR 0.52 [0.13, 2.12]	29 studies · 2375 participants	Very low
Channelled videolaryngoscopy vs direct laryngoscopy Time for tracheal intubation · adults undergoing tracheal intubation Videolaryngoscopy versus direct laryngoscopy for adults undergoing tracheal intubation (2022) · Cochrane	no estimate extracted	57 studies · 5676 participants	Very low
Macintosh‐style videolaryngoscopy vs direct laryngoscopy Dental trauma · adults undergoing tracheal intubation Videolaryngoscopy versus direct laryngoscopy for adults undergoing tracheal intubation (2022) · Cochrane	RR 0.68 [0.16, 2.89]	18 studies · 2297 participants	Very low
Macintosh‐style videolaryngoscopy vs direct laryngoscopy Time for tracheal intubation · adults undergoing tracheal intubation Videolaryngoscopy versus direct laryngoscopy for adults undergoing tracheal intubation (2022) · Cochrane	no estimate extracted	35 studies · 4061 participants	Very low
Intervention NR Time to first analgesic request (mean time in minutes) · adults undergoing surgery Pre‐emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery (2021) · Cochrane	no estimate extracted	8 studies · 410 participants	Very low
Intervention NR Adverse events · adults undergoing surgery Pre‐emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery (2021) · Cochrane	no estimate extracted	NR	No studies

Reviews 125

Perioperative fluid volume optimization following proximal femoral fracture

Lewis, SR, Butler, AR, et al. · Cochrane Database of Systematic Reviews · 2016

Anaesthesia

Thinnest evidence

Reviews 125

Perioperative fluid volume optimization following proximal femoral fracture

Fast‐track cardiac care for adult cardiac surgical patients

Single, double or multiple‐injection techniques for non‐ultrasound guided axillary brachial plexus block in adults undergoing surgery of the lower arm

Epidural pain relief versus systemic opioid‐based pain relief for abdominal aortic surgery

Hyperbaric versus isobaric bupivacaine for spinal anaesthesia for caesarean section

Hypertonic salt solution for peri‐operative fluid management

Supplemental oxygen for caesarean section during regional anaesthesia

Deliberate hypotension with propofol under anaesthesia for functional endoscopic sinus surgery (FESS)

High initial concentration versus low initial concentration sevoflurane for inhalational induction of anaesthesia

Antifibrinolytic agents for reducing blood loss in scoliosis surgery in children

Anaesthetic interventions for prevention of awareness during surgery

Lidocaine for reducing propofol‐induced pain on induction of anaesthesia in adults

Psychological preparation and postoperative outcomes for adults undergoing surgery under general anaesthesia

Active body surface warming systems for preventing complications caused by inadvertent perioperative hypothermia in adults

Paravertebral block versus thoracic epidural for patients undergoing thoracotomy

Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing mortality and morbidity in adults

Pharmacological and non‐pharmacological interventions for reducing rocuronium bromide induced pain on injection in children and adults

Vapocoolants (cold spray) for pain treatment during intravenous cannulation

Intranasal or transdermal nicotine for the treatment of postoperative pain

Intravenous nutrients for preventing inadvertent perioperative hypothermia in adults

Spectral entropy monitoring for adults and children undergoing general anaesthesia

Perioperative dexmedetomidine for acute pain after abdominal surgery in adults

Intravenous versus inhalational techniques for rapid emergence from anaesthesia in patients undergoing brain tumour surgery

Nitrates for the prevention of cardiac morbidity and mortality in patients undergoing non‐cardiac surgery

Nitrous oxide‐based versus nitrous oxide‐free general anaesthesia and accidental awareness during general anaesthesia in surgical patients