Cochrane · systematic review · CD010358
Perioperative dexmedetomidine for acute pain after abdominal surgery in adults
Jessen Lundorf, L, Korvenius Nedergaard, H, Møller, AM · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 3 · 42.9%Low 3 · 42.9%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: adults having abdominal surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Amount of 'rescue' opioid (intravenous morphine equivalents, mg) | no estimate extracted | 4 studies · 259 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Postoperative pain (VAS 0 to 100 mm, visual analogue scale from 0 = no pain to 100 = worst imaginable pain) | no estimate extracted | 4 studies · 259 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Postoperative sedation 12 hours after surgery (units of RSS, Ramsay Sedation Scale from 1 = Anxious or agitated or restless to 6 = Unresponsive) (MD, 95% CI) | no estimate extracted | 1 study · 80 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Postoperative nausea and vomiting (PONV) (RR, 95% CI) | no estimate extracted | 3 studies · 217 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Time to first passage of flatus (hours, MD, 95% CI) | no estimate extracted | 1 study · 77 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Time to first passage of stool (hours, MD, 95% CI) | no estimate extracted | NR | No studies |
Time to first out‐of‐bed mobilization (hours, MD, 95% CI) | no estimate extracted | 1 study · 77 participants | Low Downgraded: risk of bias, imprecision, inconsistency |