Cochrane · systematic review · CD009484
Vapocoolants (cold spray) for pain treatment during intravenous cannulation
Griffith, RJ, Jordan, V, Herd, D, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 25%Moderate 3 · 75%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Vapocoolant compared with placebo/no treatment for pain treatment during intravenous cannulation
Population: pain treatment during intravenous cannulation
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain during cannulation Vapocoolant vs placebo/no treatment | no estimate extracted | 8 studies · 848 participants | Moderate Downgraded: risk of bias |
Pain at application Vapocoolant vs placebo/no treatment | no estimate extracted | 4 studies · 461 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
First attempt success Vapocoolant vs placebo/no treatment | RR 1 [0.94, 1.06] | 6 studies · 812 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Adverse events Vapocoolant vs placebo/no treatment | no estimate extracted | 5 studies · 551 participants | Low Downgraded: risk of bias, imprecision, inconsistency |