Cochrane · systematic review · CD009121

Paravertebral block versus thoracic epidural for patients undergoing thoracotomy

Yeung, JHY, Gates, S, Naidu, BV, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
11
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 27.3%Moderate 8 · 72.7%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Paravertebral blockade compared to thoracic epidural blockade for patients undergoing thoracotomy (30‐day mortality and major complications)

Population: Patients undergoing thoracotomy
4 questions
OutcomeEffectEvidenceStatus / GRADE
30‐day mortality
Paravertebral blockade vs thoracic epidural blockade
RR 1.28 [0.39, 4.24]2 studies · 125 participantsLow
Downgraded: imprecision
Cardiovascular complications
Paravertebral blockade vs thoracic epidural blockade
RR 0.3 [0.01, 6.62]2 studies · 114 participantsLow
Downgraded: imprecision
Respiratory complications
Paravertebral blockade vs thoracic epidural blockade
RR 0.62 [0.26, 1.52]5 studies · 280 participantsLow
Downgraded: imprecision
Neurological complication (Delirium)
Paravertebral blockade vs thoracic epidural blockade
RR 0.3 [0.09, 0.99]2 studies · 125 participantsModerate
Downgraded: imprecision

Paravertebral blockade compared to thoracic epidural blockade for patients undergoing thoracotomy (acute pain)

Population: Patients undergoing thoracotomy
7 questions
OutcomeEffectEvidenceStatus / GRADE
VAS score at 2 ‐ 6 hours (at rest) Score from 0 ‐ 10
Paravertebral blockade vs thoracic epidural blockade
no estimate extracted6 studies · 239 participantsModerate
Downgraded: risk of bias
VAS score at 2 ‐ 6 hours (on coughing/after physiotherapy) Score from 0 ‐ 10
Paravertebral blockade vs thoracic epidural blockade
no estimate extracted3 studies · 126 participantsModerate
Downgraded: risk of bias
VAS score at 24 hours (at rest) Score from 0 ‐ 10
Paravertebral blockade vs thoracic epidural blockade
no estimate extracted6 studies · 239 participantsModerate
Downgraded: risk of bias
VAS score at 24 hours (on coughing/after physiotherapy) Score from 0 ‐ 10
Paravertebral blockade vs thoracic epidural blockade
no estimate extracted3 studies · 126 participantsModerate
Downgraded: risk of bias
VAS scores at 48 hours (at rest) Score from 0 ‐ 10
Paravertebral blockade vs thoracic epidural blockade
no estimate extracted5 studies · 220 participantsModerate
Downgraded: risk of bias
VAS scores at 48 hours (on coughing/after physiotherapy) Score from 0 ‐ 10
Paravertebral blockade vs thoracic epidural blockade
no estimate extracted3 studies · 126 participantsModerate
Downgraded: risk of bias
Failure of technique (Number of participants)
Paravertebral blockade vs thoracic epidural blockade
RR 0.27 [0.09, 0.86]4 studies · 199 participantsModerate
Downgraded: risk of bias