Cochrane · systematic review · CD007874
Lidocaine for reducing propofol‐induced pain on induction of anaesthesia in adults
Euasobhon, P, Dej‐arkom, S, Siriussawakul, A, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 20%Moderate 0 · 0%High 4 · 80%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Lidocaine for propofol‐induced pain on induction of anaesthesia in adults
Population: Adult participants receiving propofol for induction of anaesthesia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
High‐intensity pain with lidocaine admixture Pain scales | OR 0.19 [0.15, 0.25] | 31 studies · 4927 participants | High |
High‐intensity pain with lidocaine pretreatment Pain scales | OR 0.13 [0.1, 0.18] | 41 studies · 3918 participants | High |
Incidence of pain with lidocaine admixture Pain scales | OR 0.19 [0.15, 0.24] | 36 studies · 5628 participants | High |
Incidence of pain with lidocaine pretreatment Pain scales | OR 0.14 [0.11, 0.18] | 50 studies · 4722 participants | High |
Adverse effects Events | no estimate extracted | 32 studies · 4007 participants | Low Downgraded: imprecision, inconsistency |