Cochrane · systematic review · CD005059

Epidural pain relief versus systemic opioid‐based pain relief for abdominal aortic surgery

Guay, J, Kopp, S · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 28.6%Moderate 3 · 42.9%High 2 · 28.6%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Epidural pain relief compared to systemic opioid‐based pain relief for abdominal aortic surgery

Population: people undergoing abdominal aortic surgery
7 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality in hospital or up to 30 days
Epidural pain relief vs systemic opioid‐based pain relief
RR 1.06 [0.6, 1.86]14 studies · 1383 participantsLow
Downgraded: risk of bias, imprecision, indirectness, publication bias
Myocardial infarction
Epidural pain relief vs systemic opioid‐based pain relief
RR 0.54 [0.3, 0.97]7 studies · 851 participantsModerate
Downgraded: risk of bias, imprecision, indirectness, publication bias
Tracheal intubation duration
Epidural pain relief vs systemic opioid‐based pain relief
no estimate extracted8 studies · 975 participantsLow
Downgraded: risk of bias, imprecision, indirectness, publication bias
Respiratory failure
Epidural pain relief vs systemic opioid‐based pain relief
RR 0.69 [0.56, 0.85]6 studies · 861 participantsModerate
Downgraded: risk of bias, imprecision, indirectness, publication bias
Gastrointestinal bleeding
Epidural pain relief vs systemic opioid‐based pain relief
OR 0.2 [0.06, 0.65]4 studies · 487 participantsHigh
Pain (VAS scores) on movement at postoperative day 1 Scale from: 0 to 10.
Epidural pain relief vs systemic opioid‐based pain relief
no estimate extracted3 studies · 162 participantsHigh
Intensive care unit length of stay
Epidural pain relief vs systemic opioid‐based pain relief
no estimate extracted3 studies · 523 participantsModerate
Downgraded: risk of bias, imprecision, indirectness, publication bias