Cochrane Review Group

Wounds

107 systematic reviews in Wounds ask 1,645 questions. 39.6% have no studies to answer them, 33.7% rest on very low certainty evidence and 4.4% reach moderate or high certainty.

Reviews

107

Questions

1,645

current versions

No studies

39.6%

Moderate or high

4.4%

No studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Search questions in Wounds

Thinnest evidence

All no studies and very low questions

Question	Effect	Evidence	Status / GRADE
UK class 2 compression hosiery vs UK class 3 compression hosiery Duration of reulceration episodes · people with healed venous leg ulcers Compression for preventing recurrence of venous ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
UK class 2 compression hosiery vs UK class 3 compression hosiery Proportion of · people with healed venous leg ulcers Compression for preventing recurrence of venous ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
UK class 2 compression hosiery vs UK class 3 compression hosiery Ulceration on the contralateral leg · people with healed venous leg ulcers Compression for preventing recurrence of venous ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
UK class 2 compression hosiery vs UK class 3 compression hosiery Comfort · people with healed venous leg ulcers Compression for preventing recurrence of venous ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
UK class 2 compression hosiery vs UK class 3 compression hosiery Adverse effects · people with healed venous leg ulcers Compression for preventing recurrence of venous ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Protein vs standard diet Side effects: at least one adverse gastrointestinal event · patients (> 65 years) following hip fracture; patients with a recent stroke Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	RR 0.7 [0.06, 7.96]	2 studies · 140 participants	Very low
Summary of findings table ‐ Protein vs standard diet Costs ‐ not reported · patients (> 65 years) following hip fracture; patients with a recent stroke Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Protein vs standard diet Health‐related quality of life ‐ not reported · patients (> 65 years) following hip fracture; patients with a recent stroke Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet Time to complete healing of pressure ulcers ‐ not reported · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure… Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet Change in area/depth/volume of pressure ulcers ‐ not reported · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure… Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet Acceptability of nutritional supplements ‐ not reported · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure… Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet Side effects: at least one adverse gastrointestinal event · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure… Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	RR 1.6 [0.59, 4.33]	1 study · 60 participants	Very low

Reviews 107

Preoperative bathing or showering with skin antiseptics to prevent surgical site infection

Webster, J, Osborne, S · Cochrane Database of Systematic Reviews · 2015

Wounds

Thinnest evidence

Reviews 107

Preoperative bathing or showering with skin antiseptics to prevent surgical site infection

Honey as a topical treatment for wounds

Use of plastic adhesive drapes during surgery for preventing surgical site infection

Ozone therapy for treating foot ulcers in people with diabetes

Growth factors for treating diabetic foot ulcers

Early versus delayed post‐operative bathing or showering to prevent wound complications

Alginate dressings for venous leg ulcers

Early versus delayed dressing removal after primary closure of clean and clean‐contaminated surgical wounds

Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery

Dressings and securement devices for central venous catheters (CVC)

Interventions for treating gas gangrene

Devices and dressings to secure peripheral venous catheters to prevent complications

Hydrogel dressings for treating pressure ulcers

Alginate dressings for treating pressure ulcers

Negative pressure wound therapy for treating leg ulcers

Tissue adhesives for closure of surgical incisions

Recombinant human growth hormone for treating burns and donor sites

Phototherapy for treating pressure ulcers

Perioperative corticosteroids for preventing complications following facial plastic surgery

Continuous versus interrupted skin sutures for non‐obstetric surgery

Subcutaneous closure versus no subcutaneous closure after non‐caesarean surgical procedures

Granulocyte‐colony stimulating factors as adjunctive therapy for diabetic foot infections

Hydrocolloid dressings for healing diabetic foot ulcers

Hydrogel dressings for healing diabetic foot ulcers

Alginate dressings for healing diabetic foot ulcers