Cochrane Review Group

Wounds

107 systematic reviews in Wounds ask 1,645 questions. 39.6% have no studies to answer them, 33.7% rest on very low certainty evidence and 4.4% reach moderate or high certainty.

Reviews

107

Questions

1,645

current versions

No studies

39.6%

Moderate or high

4.4%

No studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Search questions in Wounds

Thinnest evidence

All no studies and very low questions

Question	Effect	Evidence	Status / GRADE
UK class 2 compression hosiery vs UK class 3 compression hosiery Duration of reulceration episodes · people with healed venous leg ulcers Compression for preventing recurrence of venous ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
UK class 2 compression hosiery vs UK class 3 compression hosiery Proportion of · people with healed venous leg ulcers Compression for preventing recurrence of venous ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
UK class 2 compression hosiery vs UK class 3 compression hosiery Ulceration on the contralateral leg · people with healed venous leg ulcers Compression for preventing recurrence of venous ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
UK class 2 compression hosiery vs UK class 3 compression hosiery Comfort · people with healed venous leg ulcers Compression for preventing recurrence of venous ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
UK class 2 compression hosiery vs UK class 3 compression hosiery Adverse effects · people with healed venous leg ulcers Compression for preventing recurrence of venous ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Protein vs standard diet Side effects: at least one adverse gastrointestinal event · patients (> 65 years) following hip fracture; patients with a recent stroke Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	RR 0.7 [0.06, 7.96]	2 studies · 140 participants	Very low
Summary of findings table ‐ Protein vs standard diet Costs ‐ not reported · patients (> 65 years) following hip fracture; patients with a recent stroke Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Protein vs standard diet Health‐related quality of life ‐ not reported · patients (> 65 years) following hip fracture; patients with a recent stroke Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet Time to complete healing of pressure ulcers ‐ not reported · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure… Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet Change in area/depth/volume of pressure ulcers ‐ not reported · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure… Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet Acceptability of nutritional supplements ‐ not reported · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure… Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet Side effects: at least one adverse gastrointestinal event · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure… Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	RR 1.6 [0.59, 4.33]	1 study · 60 participants	Very low

Reviews 107

Compression for preventing recurrence of venous ulcers

de Moraes Silva, MA, Nelson, A, et al. · Cochrane Database of Systematic Reviews · 2024

Wounds

Thinnest evidence

Reviews 107

Compression for preventing recurrence of venous ulcers

Nutritional interventions for preventing and treating pressure ulcers

Debridement for surgical wounds

Dressings and securement devices to prevent complications for peripheral arterial catheters

Interventions for postburn pruritus

Pressure‐garment therapy for preventing hypertrophic scarring after burn injury

Midline and off‐midline wound closure methods after surgical treatment for pilonidal sinus

Endovenous ablation for venous leg ulcers

Negative pressure wound therapy for treating pressure ulcers

Dressings and topical agents containing hyaluronic acid for chronic wound healing

Hydrogel dressings for donor sites of split‐thickness skin grafts

Silicone gel sheeting for treating keloid scars

Water for wound cleansing

Negative pressure wound therapy for surgical wounds healing by primary closure

Hydrogel dressings for venous leg ulcers

Laser therapy for treating hypertrophic and keloid scars

Reconstructive surgery for treating pressure ulcers

Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal pilonidal sinus

Negative pressure wound therapy for managing the open abdomen in non‐trauma patients

Preoperative hair removal to reduce surgical site infection

Wound cleansing for treating venous leg ulcers

Patient and lay carer education for preventing pressure ulceration in at‐risk populations

Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes

Silicone gel sheeting for treating hypertrophic scars

Compression bandages or stockings versus no compression for treating venous leg ulcers