Cochrane · systematic review · CD013878
Silicone gel sheeting for treating keloid scars
Tian, F, Jiang, Q, Chen, J, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
WoundsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
18
current version
GRADE rated
6
No studies
12
Included studies
NR
No studies 12 · 66.7%Ungraded 0 · 0%Very low 6 · 33.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Silicone gel sheeting compared with no treatment
Population: people with keloid scars
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Scar severity assessed by health professionals Silicone gel sheeting vs no treatment | no estimate extracted | 2 studies · 33 participants | Very low |
Scar severity validated by participants Silicone gel sheeting vs no treatment | no estimate extracted | NR | No studies |
Adverse events Silicone gel sheeting vs no treatment | no estimate extracted | NR | No studies |
Pain Silicone gel sheeting vs no treatment | no estimate extracted | 2 studies · 21 participants | Very low |
Adherence to treatment Silicone gel sheeting vs no treatment | no estimate extracted | NR | No studies |
Health‐related quality of life Silicone gel sheeting vs no treatment | no estimate extracted | NR | No studies |
Silicone gel sheeting compared with non‐silicone gel sheeting treatment
Population: people with keloid scars
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Scar severity assessed by health professionals Silicone gel sheeting vs non‐silicone gel sheeting treatment | no estimate extracted | 1 study · 16 participants | Very low |
Scar severity validated by participants Silicone gel sheeting vs non‐silicone gel sheeting treatment | no estimate extracted | NR | No studies |
Adverse events Silicone gel sheeting vs non‐silicone gel sheeting treatment | no estimate extracted | NR | No studies |
Pain Silicone gel sheeting vs non‐silicone gel sheeting treatment | no estimate extracted | 1 study · 16 participants | Very low |
Adherence to treatment Silicone gel sheeting vs non‐silicone gel sheeting treatment | no estimate extracted | NR | No studies |
Health‐related quality of life Silicone gel sheeting vs non‐silicone gel sheeting treatment | no estimate extracted | NR | No studies |
Silicone gel sheeting compared with intralesional injections of triamcinolone acetonide
Population: people with keloid scars
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Scar severity assessed by health professionals Silicone gel sheeting vs intralesional injections of triamcinolone acetonide | no estimate extracted | 1 study · 17 participants | Very low |
Scar severity validated by participants Silicone gel sheeting vs intralesional injections of triamcinolone acetonide | no estimate extracted | NR | No studies |
Adverse events Silicone gel sheeting vs intralesional injections of triamcinolone acetonide | no estimate extracted | NR | No studies |
Pain assessed using a 5‐point scale defined by study authors (0 = none, 4 = severe) Silicone gel sheeting vs intralesional injections of triamcinolone acetonide | no estimate extracted | 1 study · 5 participants | Very low |
Adherence to treatment Silicone gel sheeting vs intralesional injections of triamcinolone acetonide | no estimate extracted | NR | No studies |
Health‐related quality of life Silicone gel sheeting vs intralesional injections of triamcinolone acetonide | no estimate extracted | NR | No studies |