Cochrane · systematic review · CD003861
Water for wound cleansing
Fernandez, R, Green, HL, Griffiths, R, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
WoundsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
35
current version
GRADE rated
13
No studies
22
Included studies
NR
No studies 22 · 62.9%Ungraded 0 · 0%Very low 9 · 25.7%Low 4 · 11.4%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Tap water compared with no wound cleansing
Population: people with anal fissures
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Infection Tap water vs no wound cleansing | no estimate extracted | NR | No studies |
Wound healing Tap water vs no wound cleansing | RR 1.04 [0.95, 1.14] | 3 studies · 148 participants | Low Downgraded: imprecision |
Reduction in wound size Tap water vs no wound cleansing | no estimate extracted | NR | No studies |
Healing rate Tap water vs no wound cleansing | no estimate extracted | NR | No studies |
Cost analysis Tap water vs no wound cleansing | no estimate extracted | NR | No studies |
Pain Tap water vs no wound cleansing | no estimate extracted | 1 study · 52 participants | Low Downgraded: imprecision |
Patient satisfaction Tap water vs no wound cleansing | no estimate extracted | 2 studies · 102 participants | Low Downgraded: imprecision |
Tap water compared with normal saline for wound cleansing
Population: people with acute and chronic wounds
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Infection Tap water vs normal saline | RR 0.84 [0.59, 1.19] | 8 studies · 2204 participants | Very low Downgraded: risk of bias, imprecision |
Wounds healed Tap water vs normal saline | RR 0.57 [0.3, 1.07] | 2 studies · 79 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Reduction in wound size Tap water vs normal saline | RR 0.97 [0.56, 1.68] | 1 study · 30 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Healing rate Tap water vs normal saline | no estimate extracted | 1 study · 61 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Cost analysis Tap water vs normal saline | no estimate extracted | 2 studies · 760 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Pain Tap water vs normal saline | no estimate extracted | NR | No studies |
Patient satisfaction Tap water vs normal saline | no estimate extracted | 1 study · 49 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Distilled water compared with normal saline for wound cleansing
Population: people with fractures
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Infection Distilled water vs normal saline | RR 0.7 [0.45, 1.09] | 2 studies · 152 participants | Very low Downgraded: risk of bias, imprecision |
Wounds healed Distilled water vs normal saline | no estimate extracted | 1 study · 97 participants | Low Downgraded: risk of bias, imprecision |
Reduction in wound size Distilled water vs normal saline | no estimate extracted | NR | No studies |
Healing rate Distilled water vs normal saline | no estimate extracted | NR | No studies |
Cost analysis Distilled water vs normal saline | no estimate extracted | NR | No studies |
Pain Distilled water vs normal saline | no estimate extracted | NR | No studies |
Patient satisfaction Distilled water vs normal saline | no estimate extracted | NR | No studies |
Cooled boiled water compared with normal saline for wound cleansing
Population: people with fractures
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Infection Cooled boiled water vs normal saline | RR 0.83 [0.37, 1.87] | 1 study · 51 participants | Very low Downgraded: risk of bias, imprecision |
Wound healing Cooled boiled water vs normal saline | no estimate extracted | NR | No studies |
Reduction in wound size Cooled boiled water vs normal saline | no estimate extracted | NR | No studies |
Healing rate Cooled boiled water vs normal saline | no estimate extracted | NR | No studies |
Cost analysis Cooled boiled water vs normal saline | no estimate extracted | NR | No studies |
Pain Cooled boiled water vs normal saline | no estimate extracted | NR | No studies |
Patient satisfaction Cooled boiled water vs normal saline | no estimate extracted | NR | No studies |
Distilled water compared with cooled boiled water for wound cleansing
Population: people with fractures
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Infection Distilled water vs cooled boiled water | RR 0.59 [0.24, 1.47] | 1 study · 66 participants | Very low Downgraded: risk of bias, imprecision |
Wound healing Distilled water vs cooled boiled water | no estimate extracted | NR | No studies |
Reduction in wound size Distilled water vs cooled boiled water | no estimate extracted | NR | No studies |
Healing rate Distilled water vs cooled boiled water | no estimate extracted | NR | No studies |
Cost analysis Distilled water vs cooled boiled water | no estimate extracted | NR | No studies |
Pain Distilled water vs cooled boiled water | no estimate extracted | NR | No studies |
Patient satisfaction Distilled water vs cooled boiled water | no estimate extracted | NR | No studies |