Cochrane · systematic review · CD013357
Silicone gel sheeting for treating hypertrophic scars
Jiang, Q, Chen, J, Tian, F, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
WoundsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
53
current version
GRADE rated
8
No studies
45
Included studies
NR
No studies 45 · 84.9%Ungraded 0 · 0%Very low 5 · 9.4%Low 3 · 5.7%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Silicone gel sheeting compared with no silicone gel sheeting for treating hypertrophic scars
Population: people with hypertrophic scars
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Scar severity assessed by health professionals with VSS score from 0 to 15 Silicone gel sheeting vs no silicone gel sheeting | no estimate extracted | 2 studies · 31 participants | Very low Downgraded: risk of bias, imprecision |
Scar severity validated by participants Silicone gel sheeting vs no silicone gel sheeting | no estimate extracted | NR | No studies |
Adverse events Silicone gel sheeting vs no silicone gel sheeting | no estimate extracted | NR | No studies |
Pain assessed by VAS score from 0 to 10 Silicone gel sheeting vs no silicone gel sheeting | no estimate extracted | 1 study · 34 participants | Low Downgraded: risk of bias, imprecision |
Adherence to treatment Silicone gel sheeting vs no silicone gel sheeting | no estimate extracted | NR | No studies |
Health‐related quality of life Silicone gel sheeting vs no silicone gel sheeting | no estimate extracted | NR | No studies |
Cost effectiveness Silicone gel sheeting vs no silicone gel sheeting | no estimate extracted | NR | No studies |
CI: Confidence interval Silicone gel sheeting vs no silicone gel sheeting | no estimate extracted | NR | No studies |
Silicone gel sheeting compared with pressure garments
Population: people with hypertrophic scars
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Scar severity assessed by health professionals Silicone gel sheeting vs pressure garments | no estimate extracted | NR | No studies |
Scar severity validated by participants Silicone gel sheeting vs pressure garments | no estimate extracted | NR | No studies |
Adverse events Silicone gel sheeting vs pressure garments | no estimate extracted | NR | No studies |
Pain assessed by VAS score from 0 to 10 Silicone gel sheeting vs pressure garments | no estimate extracted | 1 study · 48 participants | Low Downgraded: risk of bias, imprecision |
Adherence to treatment Silicone gel sheeting vs pressure garments | no estimate extracted | NR | No studies |
Health‐related quality of life Silicone gel sheeting vs pressure garments | no estimate extracted | NR | No studies |
Cost effectiveness Silicone gel sheeting vs pressure garments | no estimate extracted | NR | No studies |
CI: Confidence interval Silicone gel sheeting vs pressure garments | no estimate extracted | NR | No studies |
Silicone gel sheeting compared with silicone gel
Population: people with hypertrophic scars
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Scar severity assessed by health professionals with VSS score from 0 to 14 Silicone gel sheeting vs silicone gel | no estimate extracted | 1 study · 20 participants | Very low Downgraded: risk of bias, imprecision |
Scar severity validated by participants Silicone gel sheeting vs silicone gel | no estimate extracted | NR | No studies |
Adverse events Silicone gel sheeting vs silicone gel | no estimate extracted | NR | No studies |
Pain Silicone gel sheeting vs silicone gel | no estimate extracted | NR | No studies |
Adherence to treatment Silicone gel sheeting vs silicone gel | no estimate extracted | NR | No studies |
Health‐related quality of life Silicone gel sheeting vs silicone gel | no estimate extracted | NR | No studies |
Cost effectiveness Silicone gel sheeting vs silicone gel | no estimate extracted | NR | No studies |
CI: Confidence interval Silicone gel sheeting vs silicone gel | no estimate extracted | NR | No studies |
Silicone gel sheeting compared with topical onion extract
Population: people with hypertrophic scars
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Scar severity assessed by health professionals with VSS score from 0 to 14 Silicone gel sheeting vs topical onion extract | no estimate extracted | 1 study · 20 participants | Low Downgraded: risk of bias, imprecision |
Scar severity validated by participants Silicone gel sheeting vs topical onion extract | no estimate extracted | NR | No studies |
Adverse events Silicone gel sheeting vs topical onion extract | no estimate extracted | NR | No studies |
Pain Silicone gel sheeting vs topical onion extract | no estimate extracted | NR | No studies |
Adherence to treatment Silicone gel sheeting vs topical onion extract | no estimate extracted | NR | No studies |
Health‐related quality of life Silicone gel sheeting vs topical onion extract | no estimate extracted | NR | No studies |
Cost effectiveness Silicone gel sheeting vs topical onion extract | no estimate extracted | NR | No studies |
CI: Confidence interval Silicone gel sheeting vs topical onion extract | no estimate extracted | NR | No studies |
Silicone gel sheeting compared with polyurethane
Population: people with hypertrophic scars
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Scar severity assessed by health professionals with scar index score from 0 to 14 Silicone gel sheeting vs polyurethane | no estimate extracted | 1 study · 55 participants | Very low Downgraded: risk of bias, imprecision |
Scar severity validated by participants Silicone gel sheeting vs polyurethane | no estimate extracted | NR | No studies |
Adverse events Silicone gel sheeting vs polyurethane | no estimate extracted | NR | No studies |
Pain Silicone gel sheeting vs polyurethane | no estimate extracted | NR | No studies |
Adherence to treatment Silicone gel sheeting vs polyurethane | no estimate extracted | NR | No studies |
Health‐related quality of life Silicone gel sheeting vs polyurethane | no estimate extracted | NR | No studies |
Cost effectiveness Silicone gel sheeting vs polyurethane | no estimate extracted | NR | No studies |
Silicone gel sheeting compared with self‐adhesive propylene glycol and hydroxyethyl cellulose sheeting
Population: people with hypertrophic scars
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Scar severity assessed by health professionals Silicone gel sheeting vs self‐adhesive propylene glycol and hydroxyethyl cellulose sheeting | no estimate extracted | NR | No studies |
Scar severity validated by participants Silicone gel sheeting vs self‐adhesive propylene glycol and hydroxyethyl cellulose sheeting | no estimate extracted | NR | No studies |
Adverse events Silicone gel sheeting vs self‐adhesive propylene glycol and hydroxyethyl cellulose sheeting | no estimate extracted | NR | No studies |
Pain assessed by modified VSS (unclear scale) Silicone gel sheeting vs self‐adhesive propylene glycol and hydroxyethyl cellulose sheeting | no estimate extracted | 1 study · 38 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Adherence to treatment Silicone gel sheeting vs self‐adhesive propylene glycol and hydroxyethyl cellulose sheeting | no estimate extracted | NR | No studies |
Health‐related quality of life Silicone gel sheeting vs self‐adhesive propylene glycol and hydroxyethyl cellulose sheeting | no estimate extracted | NR | No studies |
Cost effectiveness Silicone gel sheeting vs self‐adhesive propylene glycol and hydroxyethyl cellulose sheeting | no estimate extracted | NR | No studies |
Silicone gel sheeting compared with Gecko Nanoplast
Population: people with hypertrophic scars
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Scar severity assessed by health professionals Silicone gel sheeting vs Gecko Nanoplast | no estimate extracted | NR | No studies |
Scar severity validated by participants Silicone gel sheeting vs Gecko Nanoplast | no estimate extracted | NR | No studies |
Adverse events Silicone gel sheeting vs Gecko Nanoplast | no estimate extracted | NR | No studies |
Pain assessed by a Patient and Observer Scar Assessment Scale from 0 to 10 Silicone gel sheeting vs Gecko Nanoplast | no estimate extracted | 1 study · 55 participants | Very low Downgraded: risk of bias, imprecision |
Adherence to treatment Silicone gel sheeting vs Gecko Nanoplast | no estimate extracted | NR | No studies |
Health‐related quality of life Silicone gel sheeting vs Gecko Nanoplast | no estimate extracted | NR | No studies |
Cost effectiveness Silicone gel sheeting vs Gecko Nanoplast | no estimate extracted | NR | No studies |