Cochrane · systematic review · CD013710

Negative pressure wound therapy for managing the open abdomen in non‐trauma patients

Cheng, Y, Wang, K, Gong, J, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library

WoundsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
6
No studies
4
Included studies
NR
No studies 4 · 40%Ungraded 0 · 0%Very low 6 · 60%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

NPWT compared with the Bogota bag for managing the open abdomen in non‐trauma patients

Population: adults with an open abdomen after surgery who have not experienced trauma
5 questions
OutcomeEffectEvidenceStatus / GRADE
Time to primary fascial closure of the abdomen
NPWT vs the Bogota bag
MD 3.61 study · 40 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Proportion of participants with successful primary fascial closure of the abdomen
NPWT vs the Bogota bag
no estimate extractedNRNo studies
Adverse events (fistulae formation)
NPWT vs the Bogota bag
RR 2 [0.2, 20.33]1 study · 40 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
All‐cause mortality
NPWT vs the Bogota bag
RR 0.71 [0.27, 1.88]1 study · 40 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Participant health‐related quality of life
NPWT vs the Bogota bag
no estimate extractedNRNo studies

Suprasorb CNP system compared with the ABThera system for managing the open abdomen in non‐trauma patients

Population: adults with an open abdomen after surgery who have not experienced trauma
5 questions
OutcomeEffectEvidenceStatus / GRADE
Time to primary fascial closure of the abdomen
Suprasorb CNP system vs the ABThera system
no estimate extractedNRNo studies
Proportion of participants with successful primary fascial closure of the abdomen
Suprasorb CNP system vs the ABThera system
RR 0.8 [0.56, 1.14]1 study · 34 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Adverse events (fistulae formation)
Suprasorb CNP system vs the ABThera system
RR 0.11 [0.01, 1.92]1 study · 34 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
All‐cause mortality
Suprasorb CNP system vs the ABThera system
RR 0.33 [0.04, 2.89]1 study · 34 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Participant health‐related quality of life
Suprasorb CNP system vs the ABThera system
no estimate extractedNRNo studies