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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,645 questions in 107 reviews · Wounds

current versions
No studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
EU class 3 compression hosiery vs no compression
Reulceration · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
RR 0.46 [0.27, 0.76]1 study · 153 participantsLow
EU class 1 compression hosiery vs EU class 2 compression hosiery
Proportion of · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extracted2014 participantsUngraded
EU class 1 compression hosiery vs EU class 2 compression hosiery
Ulceration on the contralateral leg · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extracted2014 participantsUngraded
EU class 1 compression hosiery vs EU class 2 compression hosiery
Noncompliance · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
RR 1.22 [0.4, 3.75]1 study · 99 participantsLow
EU class 1 compression hosiery vs EU class 2 compression hosiery
Comfort · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extracted2014 participantsUngraded
EU class 1 compression hosiery vs EU class 2 compression hosiery
Adverse effects · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extracted2014 participantsUngraded
UK class 2 compression hosiery vs UK class 3 compression hosiery
Reulceration · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
RR 1.55 [1.26, 1.91]5 studies · 1314 participantsLow
UK class 2 compression hosiery vs UK class 3 compression hosiery
Duration of reulceration episodes · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extractedNRNo studies
UK class 2 compression hosiery vs UK class 3 compression hosiery
Proportion of · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extractedNRNo studies
UK class 2 compression hosiery vs UK class 3 compression hosiery
Ulceration on the contralateral leg · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extractedNRNo studies
UK class 2 compression hosiery vs UK class 3 compression hosiery
Noncompliance · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
RR 0.69 [0.49, 0.99]5 studies · 1372 participantsLow
EU class 3 compression hosiery vs no compression
Duration of reulceration episodes · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extracted2000 participantsUngraded
UK class 2 compression hosiery vs UK class 3 compression hosiery
Comfort · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extractedNRNo studies
UK class 2 compression hosiery vs UK class 3 compression hosiery
Adverse effects · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Reulceration · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
RR 0.77 [0.47, 1.28]1 study · 166 participantsLow
Intervention NR
Duration of reulceration episodes · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extracted1995 participantsUngraded
Intervention NR
Proportion of · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extracted1995 participantsUngraded
Intervention NR
Ulceration on the contralateral leg · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extracted1995 participantsUngraded
Intervention NR
Noncompliance · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
RR 0.97 [0.84, 1.12]1 study · 166 participantsLow
Intervention NR
Comfort · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extracted1995 participantsUngraded
Intervention NR
Adverse effects · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extracted1995 participantsUngraded
EU class 3 compression hosiery vs no compression
Proportion of · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extracted2000 participantsUngraded
EU class 3 compression hosiery vs no compression
Ulceration on the contralateral leg · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extracted2000 participantsUngraded
EU class 3 compression hosiery vs no compression
Noncompliance · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extracted2000 participantsUngraded
EU class 3 compression hosiery vs no compression
Comfort · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extracted2000 participantsUngraded
EU class 3 compression hosiery vs no compression
Adverse effects · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extracted2000 participantsUngraded
EU class 1 compression hosiery vs EU class 2 compression hosiery
Reulceration · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
RR 1.7 [0.67, 4.32]1 study · 99 participantsLow
EU class 1 compression hosiery vs EU class 2 compression hosiery
Duration of reulceration episodes · people with healed venous leg ulcers
Compression for preventing recurrence of venous ulcers (2024) · Cochrane
no estimate extracted2014 participantsUngraded
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet
Incidence of pressure ulcers · inpatients who are mildly or seriously malnourished or at risk of being malnourished, elderly patients at risk of…
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
RR 0.92 [0.71, 1.19]3 studies · 1634 participantsLow
Summary of findings table ‐ Protein vs standard diet
Side effects: at least one adverse gastrointestinal event · patients (> 65 years) following hip fracture; patients with a recent stroke
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
RR 0.7 [0.06, 7.96]2 studies · 140 participantsVery low
Summary of findings table ‐ Protein vs standard diet
Costs ‐ not reported · patients (> 65 years) following hip fracture; patients with a recent stroke
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Protein vs standard diet
Health‐related quality of life ‐ not reported · patients (> 65 years) following hip fracture; patients with a recent stroke
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet
Pressure ulcers healed · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure…
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
RR 1.45 [1.14, 1.85]3 studies · 577 participantsLow
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet
Time to complete healing of pressure ulcers ‐ not reported · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure…
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet
Change in area/depth/volume of pressure ulcers ‐ not reported · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure…
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet
Acceptability of nutritional supplements ‐ not reported · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure…
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet
Side effects: at least one adverse gastrointestinal event · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure…
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
RR 1.6 [0.59, 4.33]1 study · 60 participantsVery low
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet
Costs ‐ not reported · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure…
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet
Health‐related quality of life ‐ not reported · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure…
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet
Time to pressure ulcer development ‐ not reported · inpatients who are mildly or seriously malnourished or at risk of being malnourished, elderly patients at risk of…
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Protein, arginine, zinc and antioxidants vs standard diet or placebo
Pressure ulcers healed · residents of long‐term care (≥ 65 years) with pressure ulcers; inpatients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
RR 1.25 [0.49, 3.15]2 studies · 61 participantsVery low
Summary of findings table ‐ Protein, arginine, zinc and antioxidants vs standard diet or placebo
Time to complete healing of pressure ulcers ‐ not reported · residents of long‐term care (≥ 65 years) with pressure ulcers; inpatients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Protein, arginine, zinc and antioxidants vs standard diet or placebo
Pressure ulcer area (absolute) · residents of long‐term care (≥ 65 years) with pressure ulcers; inpatients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extracted2 studies · 71 participantsVery low
Summary of findings table ‐ Protein, arginine, zinc and antioxidants vs standard diet or placebo
Acceptability of nutritional supplements ‐ not reported · residents of long‐term care (≥ 65 years) with pressure ulcers; inpatients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Protein, arginine, zinc and antioxidants vs standard diet or placebo
Side effects: at least one adverse gastrointestinal event · residents of long‐term care (≥ 65 years) with pressure ulcers; inpatients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
RR 1.17 [0.77, 1.79]1 study · 43 participantsVery low
Summary of findings table ‐ Protein, arginine, zinc and antioxidants vs standard diet or placebo
Costs ‐ not reported · residents of long‐term care (≥ 65 years) with pressure ulcers; inpatients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Protein, arginine, zinc and antioxidants vs standard diet or placebo
Health‐related quality of life ‐ not reported · residents of long‐term care (≥ 65 years) with pressure ulcers; inpatients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Arginine and micronutrients vs standard diet
Pressure ulcers healed · malnourished patients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
RR 1.67 [0.8, 3.46]1 study · 200 participantsLow
Summary of findings table ‐ Arginine and micronutrients vs standard diet
Time to complete healing of pressure ulcers ‐ not reported · malnourished patients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Arginine and micronutrients vs standard diet
Change in pressure ulcer area (cm²) · malnourished patients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extracted1 study · 31 participantsLow