Cochrane · systematic review · CD010738

Hydrogel dressings for venous leg ulcers

Ribeiro, CTD, Dias, FAL, Fregonezi, GAF · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library

WoundsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
24
current version
GRADE rated
6
No studies
18
Included studies
NR
No studies 18 · 75%Ungraded 0 · 0%Very low 6 · 25%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Hydrogel dressings compared with gauze and saline for venous leg ulcers healing

Population: people with venous leg ulcers
6 questions
OutcomeEffectEvidenceStatus / GRADE
Complete wound healing
Hydrogel dressings vs gauze and saline
RR 5.33 [1.73, 16.42]1 study · 60 participantsVery low
Downgraded: risk of bias, imprecision
Incidence of wound infection
Hydrogel dressings vs gauze and saline
no estimate extractedNRNo studies
Changes in ulcer size (cm²)
Hydrogel dressings vs gauze and saline
MD 1.51 study · 60 participantsVery low
Downgraded: risk of bias, imprecision
Time‐to‐ulcer healingÂ
Hydrogel dressings vs gauze and saline
no estimate extractedNRNo studies
Health‐related quality of life
Hydrogel dressings vs gauze and saline
no estimate extractedNRNo studies
Costs
Hydrogel dressings vs gauze and saline
no estimate extractedNRNo studies

Hydrogel dressings compared with alginate gel for venous leg ulcers healing

Population: people with venous leg ulcers
6 questions
OutcomeEffectEvidenceStatus / GRADE
Complete wound healing
Hydrogel dressings vs alginate gel
no estimate extractedNRNo studies
Incidence of wound infection
Hydrogel dressings vs alginate gel
no estimate extractedNRNo studies
Change in ulcer size: percent reduction in ulcer area at 4 weeks
Hydrogel dressings vs alginate gel
MD 41.81 study · 20 participantsVery low
Downgraded: risk of bias, imprecision
Time‐to‐ulcer healing
Hydrogel dressings vs alginate gel
no estimate extractedNRNo studies
Health‐related quality of life
Hydrogel dressings vs alginate gel
no estimate extractedNRNo studies
Costs
Hydrogel dressings vs alginate gel
no estimate extractedNRNo studies

Hydrogel dressings compared with manuka honey for venous leg ulcers healing

Population: people with venous leg ulcers
6 questions
OutcomeEffectEvidenceStatus / GRADE
Complete wound healing
Hydrogel dressings vs manuka honey
RR 0.75 [0.46, 1.21]1 study · 108 participantsVery low
Downgraded: risk of bias, imprecision
Incidence of wound infection
Hydrogel dressings vs manuka honey
RR 2 [0.81, 4.94]1 study · 108 participantsVery low
Downgraded: risk of bias, imprecision
Change in ulcer size
Hydrogel dressings vs manuka honey
no estimate extractedNRNo studies
Time‐to‐ulcer healingÂ
Hydrogel dressings vs manuka honey
no estimate extractedNRNo studies
Health‐related quality of life
Hydrogel dressings vs manuka honey
no estimate extractedNRNo studies
CostsÂ
Hydrogel dressings vs manuka honey
no estimate extractedNRNo studies

Hydrogel dressing compared with hydrocolloid for venous ulcer healing

Population: people with venous leg ulcers
6 questions
OutcomeEffectEvidenceStatus / GRADE
Complete ulcer healing
Hydrogel dressing vs hydrocolloid
no estimate extractedNRNo studies
Incidence of wound infection
Hydrogel dressing vs hydrocolloid
no estimate extractedNRNo studies
Change in ulcer size
Hydrogel dressing vs hydrocolloid
no estimate extracted1 study · 84 participantsVery low
Downgraded: risk of bias, imprecision
Time‐to‐ulcer healingÂ
Hydrogel dressing vs hydrocolloid
no estimate extractedNRNo studies
Health‐related quality of life
Hydrogel dressing vs hydrocolloid
no estimate extractedNRNo studies
Costs
Hydrogel dressing vs hydrocolloid
no estimate extractedNRNo studies