Cochrane Review Group

Wounds

107 systematic reviews in Wounds ask 1,645 questions. 39.6% have no studies to answer them, 33.7% rest on very low certainty evidence and 4.4% reach moderate or high certainty.

Reviews

107

Questions

1,645

current versions

No studies

39.6%

Moderate or high

4.4%

No studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Search questions in Wounds

Thinnest evidence

All no studies and very low questions

Question	Effect	Evidence	Status / GRADE
UK class 2 compression hosiery vs UK class 3 compression hosiery Duration of reulceration episodes · people with healed venous leg ulcers Compression for preventing recurrence of venous ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
UK class 2 compression hosiery vs UK class 3 compression hosiery Proportion of · people with healed venous leg ulcers Compression for preventing recurrence of venous ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
UK class 2 compression hosiery vs UK class 3 compression hosiery Ulceration on the contralateral leg · people with healed venous leg ulcers Compression for preventing recurrence of venous ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
UK class 2 compression hosiery vs UK class 3 compression hosiery Comfort · people with healed venous leg ulcers Compression for preventing recurrence of venous ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
UK class 2 compression hosiery vs UK class 3 compression hosiery Adverse effects · people with healed venous leg ulcers Compression for preventing recurrence of venous ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Protein vs standard diet Side effects: at least one adverse gastrointestinal event · patients (> 65 years) following hip fracture; patients with a recent stroke Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	RR 0.7 [0.06, 7.96]	2 studies · 140 participants	Very low
Summary of findings table ‐ Protein vs standard diet Costs ‐ not reported · patients (> 65 years) following hip fracture; patients with a recent stroke Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Protein vs standard diet Health‐related quality of life ‐ not reported · patients (> 65 years) following hip fracture; patients with a recent stroke Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet Time to complete healing of pressure ulcers ‐ not reported · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure… Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet Change in area/depth/volume of pressure ulcers ‐ not reported · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure… Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet Acceptability of nutritional supplements ‐ not reported · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure… Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	no estimate extracted	NR	No studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet Side effects: at least one adverse gastrointestinal event · long‐term care patients; inpatients without dehydration with energy intake by tube feeding; patients with pressure… Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane	RR 1.6 [0.59, 4.33]	1 study · 60 participants	Very low

Reviews 107

Scalpel versus electrosurgery for major abdominal incisions

Charoenkwan, K, Iheozor‐Ejiofor, Z, et al. · Cochrane Database of Systematic Reviews · 2017

Wounds

Thinnest evidence

Reviews 107

Scalpel versus electrosurgery for major abdominal incisions

Topical phenytoin for treating pressure ulcers

Topical antimicrobial agents for treating foot ulcers in people with diabetes

Foam dressings for treating pressure ulcers

Anabolic steroids for treating pressure ulcers

Systemic antibiotics for treating malignant wounds

Antiseptics for burns

Fibrin glue for pilonidal sinus disease

Dressings and topical agents for treating pressure ulcers

Phototherapy for treating foot ulcers in people with diabetes

Intracavity lavage and wound irrigation for prevention of surgical site infection

Nasal decontamination for the prevention of surgical site infection in Staphylococcus aureus carriers

Dressings for the prevention of surgical site infection

Autologous platelet‐rich plasma for treating chronic wounds

Interventions for helping people adhere to compression treatments for venous leg ulceration

Frequency of dressing changes for central venous access devices on catheter‐related infections

Oral aspirin for treating venous leg ulcers

Skin antisepsis for reducing central venous catheter‐related infections

Sulodexide for treating venous leg ulcers

Wound drainage for lower limb arterial surgery

Internal dressings for healing perianal abscess cavities

Skin grafting and tissue replacement for treating foot ulcers in people with diabetes

Topical antibiotics for preventing surgical site infection in wounds healing by primary intention

Protease‐modulating matrix treatments for healing venous leg ulcers

Hyperbaric oxygen therapy for chronic wounds