Cochrane · systematic review · CD009213

Frequency of dressing changes for central venous access devices on catheter‐related infections

Gavin, NC, Webster, J, Chan, RJ, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

WoundsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 25%Low 3 · 75%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Longer intervals (5‐15 days) (intervention) versus shorter intervals (2‐5 days) (control) between dressing changes for preventing catheter‐related infection in people with central venous access devices

Population: patients with a central venous access device
4 questions
OutcomeEffectEvidenceStatus / GRADE
Catheter‐related blood stream infection (CRBSI)
Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes
RR 1.42 [0.4, 4.98]NRLow
Downgraded: risk of bias
All‐cause mortality
Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes
RR 1.06 [0.9, 1.25]NRLow
Downgraded: risk of bias, imprecision, inconsistency
Skin damage № of participants: 1587 (4 RCTs)
Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision, inconsistency
Pain № of participants: 193 (2 RCTs)
Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes
RR 0.8 [0.46, 1.38]NRLow
Downgraded: risk of bias