Cochrane · systematic review · CD011923

Fibrin glue for pilonidal sinus disease

Lund, J, Tou, S, Doleman, B, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

WoundsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
3
No studies
3
Included studies
NR
No studies 3 · 50%Ungraded 0 · 0%Very low 3 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Fibrin glue compared with Bascom's procedure for pilonidal sinus

Population: adults with pilonidal sinus
2 questions
OutcomeEffectEvidenceStatus / GRADE
Time to healing (days)
Fibrin glue vs Bascom's procedure
no estimate extractedNRNo studies
Adverse events (seroma or allergic reaction)
Fibrin glue vs Bascom's procedure
no estimate extractedNRNo studies

Limberg flap plus fibrin glue compared with Limberg flap for pilonidal sinus

Population: Men with pilonidal sinus
2 questions
OutcomeEffectEvidenceStatus / GRADE
Time to healing (days)
Limberg flap plus fibrin glue vs Limberg flap
no estimate extracted1 study · 132 participantsVery low
Downgraded: risk of bias, imprecision
Adverse event (seroma)
Limberg flap plus fibrin glue vs Limberg flap
RR 0.27 [0.05, 1.63]2 studies · 164 participantsVery low
Downgraded: risk of bias, imprecision

Karydakis flap plus fibrin glue compared with Karydakis flap and drain for pilonidal sinus

Population: Men with pilonidal sinus
2 questions
OutcomeEffectEvidenceStatus / GRADE
Time to healing (days)
Karydakis flap plus fibrin glue vs Karydakis flap and drain
no estimate extractedNRNo studies
Adverse event (seroma)
Karydakis flap plus fibrin glue vs Karydakis flap and drain
RR 3 [0.67, 13.46]1 study · 50 participantsVery low
Downgraded: risk of bias, imprecision