Cochrane · systematic review · CD011947

Dressings and topical agents for treating pressure ulcers

Westby, MJ, Dumville, JC, Soares, MO, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

WoundsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
19
current version
GRADE rated
18
No studies
1
Included studies
NR
No studies 1 · 5.3%Ungraded 0 · 0%Very low 13 · 68.4%Low 4 · 21.1%Moderate 1 · 5.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

NMA evidence for individual network: proportion with complete healing ‐ interventions versus saline gauze

Population: people with pressure ulcers
19 questions
OutcomeEffectEvidenceStatus / GRADE
Contrasts: interventions versus saline gauze
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
no estimate extractedNRNo studies
Alginate dressings
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 1.09 [0.11, 10.57]NRVery low
Downgraded: risk of bias, imprecision
Sequential hydrocolloid alginate dressings
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 0.5 [0.12, 1.98]NRVery low
Downgraded: risk of bias, imprecision
Basic wound contact dressings
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 1.3 [0.65, 2.58]NRLow
Downgraded: imprecision
Collagenase ointment
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 2.12 [1.06, 4.22]NRLow
Downgraded: risk of bias, imprecision
Dextranomer
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 4.76 [0.86, 26.39]NRVery low
Downgraded: risk of bias, imprecision
Foam dressings
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 1.52 [1.03, 2.26]NRLow
Downgraded: risk of bias, imprecision
Hydrocolloid dressing with/without alginate
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 1.22 [0.06, 24.74]NRVery low
Downgraded: risk of bias, imprecision
Hydrocolloid dressings
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 1.43 [1, 2.05]NRVery low
Downgraded: risk of bias, imprecision, inconsistency
Hydrogel
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 1.55 [1.02, 2.36]NRVery low
Downgraded: risk of bias, imprecision, inconsistency
Iodine‐containing dressings
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 1.08 [0.58, 2.03]NRVery low
Downgraded: risk of bias, imprecision
Phenytoin
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 1.27 [0.58, 2.8]NRVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Protease‐modulating dressings
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 1.65 [0.92, 2.94]NRModerate
Downgraded: imprecision
Polyvinylpyrrolidone + zinc oxide
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 1.31 [0.37, 4.62]NRLow
Downgraded: imprecision
Combination silicone foam dressings
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 1.93 [0.38, 9.98]NRVery low
Downgraded: risk of bias, imprecision
Soft polymer dressings
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 1.35 [0.55, 3.27]NRVery low
Downgraded: risk of bias, imprecision
Sugar + egg white
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 0.7 [0.03, 15.62]NRVery low
Downgraded: risk of bias, imprecision
Tripeptide copper gel
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 3.9 [1.04, 14.63]NRVery low
Downgraded: risk of bias, imprecision
Vapour‐permeable dressings
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
RR 1.45 [0.74, 2.81]NRVery low
Downgraded: risk of bias, imprecision