Cochrane · systematic review · CD008251
Topical phenytoin for treating pressure ulcers
Hao, XY, Li, HL, Su, H, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
WoundsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
2
No studies
5
Included studies
NR
No studies 5 · 41.7%Ungraded 5 · 41.7%Very low 1 · 8.3%Low 1 · 8.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Topical phenytoin compared with hydrocolloid dressing for pressure ulcers
Population: people with a pressure ulcer
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time to complete healing Topical phenytoin vs hydrocolloid dressing | no estimate extracted | NR | No studies |
Proportion of ulcers healed within trial period (eight weeks) Topical phenytoin vs hydrocolloid dressing | RR 0.55 [0.33, 0.92] | 1 study · 56 participants | Low Downgraded: risk of bias, imprecision |
Adverse events Topical phenytoin vs hydrocolloid dressing | no estimate extracted | 2 studies · 84 participants | Ungraded |
Pain Topical phenytoin vs hydrocolloid dressing | no estimate extracted | 1 study · 28 participants | Ungraded |
Topical phenytoin compared with triple antibiotic ointment for pressure ulcers
Population: people with a pressure ulcer
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time to complete healing Topical phenytoin vs triple antibiotic ointment | no estimate extracted | NR | No studies |
Proportion of ulcers healed within trial period (eight weeks) Topical phenytoin vs triple antibiotic ointment | no estimate extracted | NR | No studies |
Adverse events Topical phenytoin vs triple antibiotic ointment | no estimate extracted | 1 study · 28 participants | Ungraded |
Pain Topical phenytoin vs triple antibiotic ointment | no estimate extracted | 1 study · 28 participants | Ungraded |
Topical phenytoin group compared with a simple dressing for pressure ulcers
Population: people with a pressure ulcer
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time to complete healing Topical phenytoin group vs a simple dressing | no estimate extracted | NR | No studies |
Proportion of ulcers healed within trial period (eight weeks) Topical phenytoin group vs a simple dressing | RR 1.33 [0.63, 2.78] | 1 study · 55 participants | Very low Downgraded: risk of bias, imprecision |
Adverse events Topical phenytoin group vs a simple dressing | no estimate extracted | 2 studies · 81 participants | Ungraded |
Pain Topical phenytoin group vs a simple dressing | no estimate extracted | NR | No studies |