Cochrane · systematic review · CD004287
Tissue adhesives for closure of surgical incisions
Dumville, JC, Coulthard, P, Worthington, HV, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
WoundsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
12
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 4 · 33.3%Low 8 · 66.7%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Tissue adhesive compared to sutures for surgical incisions
Population: People with surgical incisions
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Wound dehiscence Tissue adhesive vs sutures | RR 3.35 [1.53, 7.32] | 10 studies · 736 participants | Low |
Wound infection Tissue adhesive vs sutures | RR 1.72 [0.92, 3.16] | 10 studies · 744 participants | Very low |
Tissue adhesive compared to adhesive tape for surgical incisions
Population: people with surgical incisions
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Wound dehiscence Tissue adhesive vs adhesive tape | RR 0.96 [0.06, 14.55] | 1 study · 50 participants | Low |
Wound infection Tissue adhesive vs adhesive tape | RR 1.37 [0.39, 4.81] | 3 studies · 190 participants | Low Downgraded: imprecision, inconsistency |
Tissue adhesive compared to staples for surgical incisions
Population: people with surgical incisions
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Wound dehiscence Tissue adhesive vs staples | RR 0.53 [0.05, 5.33] | 1 study · 37 participants | Low |
Wound infection Tissue adhesive vs staples | RR 1.39 [0.3, 6.54] | 3 studies · 250 participants | Very low Downgraded: imprecision |
Tissue adhesive compared to other methods for surgical incisions
Population: people with surgical incisions
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Wound dehiscence Tissue adhesive vs other methods | RR 0.55 [0.13, 2.38] | 1 study · 209 participants | Low Downgraded: imprecision |
Wound infection Tissue adhesive vs other methods | RR 0.41 [0.11, 1.6] | 1 study · 209 participants | Low Downgraded: imprecision |
High viscosity tissue adhesive compared to low viscosity tissue adhesive for surgical incisions
Population: people with surgical incisions
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Wound dehiscence High viscosity tissue adhesive vs low viscosity tissue adhesive | RR 3.74 [0.21, 67.93] | 1 study · 148 participants | Very low Downgraded: imprecision |
Wound infection High viscosity tissue adhesive vs low viscosity tissue adhesive | RR 0.82 [0.16, 4.31] | 1 study · 148 participants | Very low Downgraded: imprecision |
Octylcyanoacrylate compared to butylcyanoacrylate for surgical incisions
Population: people with surgical incisions
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Wound dehiscence Octylcyanoacrylate vs butylcyanoacrylate | RR 1.46 [0.19, 11] | 2 studies · 80 participants | Low |
Wound infection Octylcyanoacrylate vs butylcyanoacrylate | RR 0.63 [0.21, 1.88] | 1 study · 37 participants | Low |