Cochrane · systematic review · CD010182

Alginate dressings for venous leg ulcers

O'Meara, S, Martyn‐St James, M, Adderley, UJ · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Wounds2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
16
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 11 · 68.8%Very low 5 · 31.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Alginate dressing (Sorbsan®) compared to alternative alginate dressing (Tegagen™ High Gelling) for venous leg ulceration

Population: people with venous leg ulceration
5 questions
OutcomeEffectEvidenceStatus / GRADE
Time to healing
Alginate dressing (Sorbsan®) vs alternative alginate dressing (Tegagen™ High Gelling)
no estimate extracted0 studies · 0 participantsUngraded
Proportion of participants with healed ulcers
Alginate dressing (Sorbsan®) vs alternative alginate dressing (Tegagen™ High Gelling)
RR 6 [0.32, 111.04]1 study · 20 participantsVery low
Downgraded: risk of bias, inconsistency, publication bias
Mean change in wound size, with adjustment for baseline size
Alginate dressing (Sorbsan®) vs alternative alginate dressing (Tegagen™ High Gelling)
no estimate extracted0 studies · 0 participantsUngraded
Adverse effects
Alginate dressing (Sorbsan®) vs alternative alginate dressing (Tegagen™ High Gelling)
no estimate extracted0 studies · 0 participantsUngraded
Health‐related quality of life
Alginate dressing (Sorbsan®) vs alternative alginate dressing (Tegagen™ High Gelling)
no estimate extracted0 studies · 0 participantsUngraded

Alginate dressing compared to hydrocolloid dressing for venous leg ulceration

Population: people with venous leg ulceration
6 questions
OutcomeEffectEvidenceStatus / GRADE
Time to healing
Alginate dressing vs hydrocolloid dressing
no estimate extracted0 studies · 0 participantsUngraded
Proportion of participants with healed ulcers at 6 weeks
Alginate dressing vs hydrocolloid dressing
RR 0.42 [0.14, 1.21]2 studies · 84 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Proportion of participants with healed ulcers at 12 weeks
Alginate dressing vs hydrocolloid dressing
RR 1.02 [0.57, 1.81]1 study · 131 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Mean change in wound size, with adjustment for baseline size
Alginate dressing vs hydrocolloid dressing
no estimate extracted0 studies · 0 participantsUngraded
Proportion of participants experiencing adverse effects at 6 weeks
Alginate dressing vs hydrocolloid dressing
RR 1.47 [0.53, 4.03]1 study · 40 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Health‐related quality of life
Alginate dressing vs hydrocolloid dressing
no estimate extracted0 studies · 0 participantsUngraded

Alginate dressing compared to plain non‐adherent dressing for venous leg ulceration

Population: people with venous leg ulceration
5 questions
OutcomeEffectEvidenceStatus / GRADE
Time to healing
Alginate dressing vs plain non‐adherent dressing
no estimate extracted0 studies · 0 participantsUngraded
Proportion of participants with healed ulcers
Alginate dressing vs plain non‐adherent dressing
RR 1.08 [0.86, 1.36]1 study · 60 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Mean change in wound size, with adjustment for baseline size
Alginate dressing vs plain non‐adherent dressing
no estimate extracted0 studies · 0 participantsUngraded
Adverse effects
Alginate dressing vs plain non‐adherent dressing
no estimate extracted0 studies · 0 participantsUngraded
Health‐related quality of life
Alginate dressing vs plain non‐adherent dressing
no estimate extracted0 studies · 0 participantsUngraded