Cochrane · systematic review · CD010182
Alginate dressings for venous leg ulcers
O'Meara, S, Martyn‐St James, M, Adderley, UJ · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
16
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 11 · 68.8%Very low 5 · 31.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyAlginate dressing (Sorbsan®) compared to alternative alginate dressing (Tegagen™ High Gelling) for venous leg ulceration
Population: people with venous leg ulceration
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time to healing Alginate dressing (Sorbsan®) vs alternative alginate dressing (Tegagen™ High Gelling) | no estimate extracted | 0 studies · 0 participants | Ungraded |
Proportion of participants with healed ulcers Alginate dressing (Sorbsan®) vs alternative alginate dressing (Tegagen™ High Gelling) | RR 6 [0.32, 111.04] | 1 study · 20 participants | Very low Downgraded: risk of bias, inconsistency, publication bias |
Mean change in wound size, with adjustment for baseline size Alginate dressing (Sorbsan®) vs alternative alginate dressing (Tegagen™ High Gelling) | no estimate extracted | 0 studies · 0 participants | Ungraded |
Adverse effects Alginate dressing (Sorbsan®) vs alternative alginate dressing (Tegagen™ High Gelling) | no estimate extracted | 0 studies · 0 participants | Ungraded |
Health‐related quality of life Alginate dressing (Sorbsan®) vs alternative alginate dressing (Tegagen™ High Gelling) | no estimate extracted | 0 studies · 0 participants | Ungraded |
Alginate dressing compared to hydrocolloid dressing for venous leg ulceration
Population: people with venous leg ulceration
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time to healing Alginate dressing vs hydrocolloid dressing | no estimate extracted | 0 studies · 0 participants | Ungraded |
Proportion of participants with healed ulcers at 6 weeks Alginate dressing vs hydrocolloid dressing | RR 0.42 [0.14, 1.21] | 2 studies · 84 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Proportion of participants with healed ulcers at 12 weeks Alginate dressing vs hydrocolloid dressing | RR 1.02 [0.57, 1.81] | 1 study · 131 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, publication bias |
Mean change in wound size, with adjustment for baseline size Alginate dressing vs hydrocolloid dressing | no estimate extracted | 0 studies · 0 participants | Ungraded |
Proportion of participants experiencing adverse effects at 6 weeks Alginate dressing vs hydrocolloid dressing | RR 1.47 [0.53, 4.03] | 1 study · 40 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, publication bias |
Health‐related quality of life Alginate dressing vs hydrocolloid dressing | no estimate extracted | 0 studies · 0 participants | Ungraded |
Alginate dressing compared to plain non‐adherent dressing for venous leg ulceration
Population: people with venous leg ulceration
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time to healing Alginate dressing vs plain non‐adherent dressing | no estimate extracted | 0 studies · 0 participants | Ungraded |
Proportion of participants with healed ulcers Alginate dressing vs plain non‐adherent dressing | RR 1.08 [0.86, 1.36] | 1 study · 60 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, publication bias |
Mean change in wound size, with adjustment for baseline size Alginate dressing vs plain non‐adherent dressing | no estimate extracted | 0 studies · 0 participants | Ungraded |
Adverse effects Alginate dressing vs plain non‐adherent dressing | no estimate extracted | 0 studies · 0 participants | Ungraded |
Health‐related quality of life Alginate dressing vs plain non‐adherent dressing | no estimate extracted | 0 studies · 0 participants | Ungraded |
Alginate dressing (Sorbsan®) compared to alternative alginate dressing (Tegagen™ High Gelling) for venous leg ulceration
Population: people with venous leg ulceration
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time to healing Alginate dressing (Sorbsan®) vs alternative alginate dressing (Tegagen™ High Gelling) | no estimate extracted | 0 studies · 0 participants | Ungraded |
Proportion of participants with healed ulcers Alginate dressing (Sorbsan®) vs alternative alginate dressing (Tegagen™ High Gelling) | RR 6 [0.32, 111.04] | 1 study · 20 participants | Very low Downgraded: risk of bias, inconsistency, publication bias |
Mean change in wound size, with adjustment for baseline size Alginate dressing (Sorbsan®) vs alternative alginate dressing (Tegagen™ High Gelling) | no estimate extracted | 0 studies · 0 participants | Ungraded |
Adverse effects Alginate dressing (Sorbsan®) vs alternative alginate dressing (Tegagen™ High Gelling) | no estimate extracted | 0 studies · 0 participants | Ungraded |
Health‐related quality of life Alginate dressing (Sorbsan®) vs alternative alginate dressing (Tegagen™ High Gelling) | no estimate extracted | 0 studies · 0 participants | Ungraded |
Alginate dressing compared to hydrocolloid dressing for venous leg ulceration
Population: people with venous leg ulceration
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time to healing Alginate dressing vs hydrocolloid dressing | no estimate extracted | 0 studies · 0 participants | Ungraded |
Proportion of participants with healed ulcers at 6 weeks Alginate dressing vs hydrocolloid dressing | RR 0.42 [0.14, 1.21] | 2 studies · 84 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Proportion of participants with healed ulcers at 12 weeks Alginate dressing vs hydrocolloid dressing | RR 1.02 [0.57, 1.81] | 1 study · 131 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, publication bias |
Mean change in wound size, with adjustment for baseline size Alginate dressing vs hydrocolloid dressing | no estimate extracted | 0 studies · 0 participants | Ungraded |
Proportion of participants experiencing adverse effects at 6 weeks Alginate dressing vs hydrocolloid dressing | RR 1.47 [0.53, 4.03] | 1 study · 40 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, publication bias |
Health‐related quality of life Alginate dressing vs hydrocolloid dressing | no estimate extracted | 0 studies · 0 participants | Ungraded |
Alginate dressing compared to plain non‐adherent dressing for venous leg ulceration
Population: people with venous leg ulceration
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time to healing Alginate dressing vs plain non‐adherent dressing | no estimate extracted | 0 studies · 0 participants | Ungraded |
Proportion of participants with healed ulcers Alginate dressing vs plain non‐adherent dressing | RR 1.08 [0.86, 1.36] | 1 study · 60 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, publication bias |
Mean change in wound size, with adjustment for baseline size Alginate dressing vs plain non‐adherent dressing | no estimate extracted | 0 studies · 0 participants | Ungraded |
Adverse effects Alginate dressing vs plain non‐adherent dressing | no estimate extracted | 0 studies · 0 participants | Ungraded |
Health‐related quality of life Alginate dressing vs plain non‐adherent dressing | no estimate extracted | 0 studies · 0 participants | Ungraded |