Cochrane · systematic review · CD010266
Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery
Brignardello‐Petersen, R, Carrasco‐Labra, A, Araya, I, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
WoundsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
3
No studies
7
Included studies
NR
No studies 7 · 70%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 20%Moderate 1 · 10%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: patients undergoing orthognathic surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Surgical site infection | RR 0.42 [0.24, 0.74] | 7 studies · 472 participants | Moderate Downgraded: risk of bias |
Systemic infection | no estimate extracted | NR | No studies |
Adverse events | no estimate extracted | NR | No studies |
Duration of hospital stay | no estimate extracted | NR | No studies |
Health‐related quality of life | no estimate extracted | NR | No studies |
Comparison
Population: patients undergoing orthognathic surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Surgical site infection | RR 0.34 [0.09, 1.22] | 2 studies · 220 participants | Low Downgraded: risk of bias |
Adverse events | no estimate extracted | 1 study · 70 participants | Low Downgraded: risk of bias, imprecision |
Systemic infection | no estimate extracted | NR | No studies |
Duration of hospital stay | no estimate extracted | NR | No studies |
Health‐related quality of life | no estimate extracted | NR | No studies |