Cochrane · systematic review · CD008474
Ozone therapy for treating foot ulcers in people with diabetes
Liu, J, Zhang, P, Tian, J, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
WoundsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 6 · 85.7%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Ozone versus antibiotic treatments for treating foot ulcers in people with diabetes
Population: patients with treating foot ulcers in people with diabetes
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Number of ulcers healed Ozone vs antibiotic treatments | RR 1.1 [0.87, 1.4] | 1 study · 100 participants | Low Downgraded: risk of bias |
Reduction in ulcer area Ozone vs antibiotic treatments | no estimate extracted | 1 study · 100 participants | Low Downgraded: risk of bias |
Length of hospitalisation Ozone vs antibiotic treatments | no estimate extracted | 1 study · 100 participants | Low Downgraded: risk of bias |
Ozone + usual care versus sham ozone + usual care for treating foot ulcers in people with diabetes
Population: patients with treating foot ulcers in people with diabetes
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Number of ulcers healed Ozone + usual care vs sham ozone + usual care | RR 1.69 [0.9, 3.17] | 2 studies · 111 participants | Low Downgraded: risk of bias |
Reduction in ulcer area Ozone + usual care vs sham ozone + usual care | no estimate extracted | 2 studies · 111 participants | Very low Downgraded: risk of bias, inconsistency |
Adverse events/complications Ozone + usual care vs sham ozone + usual care | RR 2.27 [0.48, 10.79] | 1 study · 61 participants | Low Downgraded: risk of bias |
amputation Ozone + usual care vs sham ozone + usual care | RR 2.73 [0.12, 64.42] | 1 study · 61 participants | Low Downgraded: risk of bias |